GLP-1 Bodybuilding Risks: Muscle Loss & Rebound Explained episode artwork

EPISODE · Mar 18, 2026 · 35 MIN

GLP-1 Bodybuilding Risks: Muscle Loss & Rebound Explained

from Peak Physique Podcast · host NASM Podcast Network

Welcome to the NASM “Peak Physique Podcast!” In this must-watch episode, IFBB Olympian and NASM Master Trainer Andre Adams dives deep into the trending world of GLP-1 drugs like Ozempic, Wegovy, and tirzepatide—now making major waves in bodybuilding and athletic fat loss. EPISODE HIGHLIGHTS: What happens after you stop taking GLP-1 medications? The real metabolic & muscle risks for bodybuilders and physique athletes How to safeguard your muscle mass while dropping fat fast Rebuilding your appetite & metabolism post-GLP Proven strategies for a successful post-competition (or post-GLP) reverse diet Who should actually avoid GLP-1 drugs? Long-term effects on hunger, hormones (leptin, ghrelin), and central nervous system health PLUS: Andre breaks down the exact mechanisms of GLPs (GLP-1, 2, and 3), how they impact gut health, insulin, glycogen, and training adaptation. Learn about common mistakes that flatten your physique, and which supplements and nutrition tweaks help restore optimal performance after coming off these medications. 💡 Perfect for anyone considering GLP-1 drugs for fat loss, competitors prepping for the stage, coaches guiding athletes, or anyone serious about functional fitness and metabolism mastery.Episode References: ·        Wilding et al., 2021 — New England Journal of Medicine Study ·        Jastreboff et al., 2022 — New England Journal of Medicine ·        Al Sulaiman et al., 2023 — Diabetes, Obesity & Metabolism If you like what you just consumed, leave us a 5-star review, and share this episode with a friend to help grow our NASM health and wellness community! The content shared in this podcast is solely for educational and entertainment purposes. It is not intended to be a substitute for professional advice, diagnosis, or treatment. Always seek out the guidance of your healthcare provider or other qualified professional. Any opinions expressed by guests and hosts are their own and do not necessarily reflect the views of NASM. Introducing NASM One, the membership for trainers and coaches. For just $35/mo., get unlimited access to over 300 continuing education courses, 50% off additional certifications and specializations, EDGE Trainer Pro all-in-one coaching app to grow your business, unlimited exam attempts and select waived fees. Stay on top of your game and ahead of the curve as a fitness professional with NASM One. Click here to learn more. https://bit.ly/4ddsgrm

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GLP-1 Bodybuilding Risks: Muscle Loss & Rebound Explained

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