GLP-1 Medications Explained: The $200 Billion Healthcare Revolution | OON Episode 19 episode artwork

EPISODE · Jan 20, 2026 · 43 MIN

GLP-1 Medications Explained: The $200 Billion Healthcare Revolution | OON Episode 19

from Out of Network Podcast · host Ryon Parker and Rishi Seth

In this episode of Out of Network, Dr. Ryon Parker and Dr. Rishi Seth dive deep into the explosive world of GLP-1 medications—exploring the realities of semaglutide, tirzepatide, Ozempic, Wegovy, and Zepbound. With a projected $200 billion market by 2029, these drugs have transformed weight management, but they've also created chaos in the healthcare landscape. From med spa injections to proper medical supervision, this conversation sheds light on what safe GLP-1 treatment should actually look like.What You'll LearnThe difference between proper medical weight loss programs and dangerous "syringe-in-a-fridge" clinicsWhy tirzepatide (Mounjaro/Zepbound) outperforms semaglutide (Ozempic) in most patientsReal strategies for patients who plateau or don't respond to GLP-1 medicationsInsurance coverage realities and the new $50/month Medicare pricingSerious side effects to watch for, including pancreatitis and gallbladder issuesTimestamps00:00 – Introduction: The $200 billion GLP-1 economy03:15 – Wild West of GLP-1 prescribing: Med spas and strip mall clinics10:42 – Proper patient screening and medical supervision24:30 – Insurance coverage, pricing, and access issues32:00 – Tirzepatide vs. Semaglutide: Which is better?42:55 – The future of GLP-1s and closing thoughtsConnect with Out of Network: 🌐 Website: https://www.outofnetworkpod.com/ 📱 Instagram: https://www.instagram.com/outofnetworkpodcast/ ▶️ YouTube: https://www.youtube.com/@OutofNetworkPodcast 🎵 TikTok: https://www.tiktok.com/@outofnetworkpodcastConnect with the Hosts:Dr. Ryon Parker → https://www.instagram.com/dr.ryonparker/Parker Medical: https://parkermedical.org/Dr. Rishi Seth → https://www.instagram.com/drrishiseth/Seth Premiere Medical: https://sethmedical.com/Enjoyed the Episode?If this conversation resonated with you, please like, comment, and subscribe. Share it with someone who cares about the future of healthcare.🎙 About Out of Network Out of Network is a bold, physician-led podcast hosted by Dr. Ryon Parker and Dr. Rishi Seth. Each week, they challenge the broken healthcare system and explore how medicine can be reimagined—through patient-first care, prevention, and real human stories.Enjoyed the Episode?If you liked this conversation, please subscribe, leave us a review, and share this podcast with a friend—it helps more people discover a new vision for healthcare.

In this episode of Out of Network, Dr. Ryon Parker and Dr. Rishi Seth dive deep into the explosive world of GLP-1 medications—exploring the realities of semaglutide, tirzepatide, Ozempic, Wegovy, and Zepbound. With a projected $200 billion market by 2029, these drugs have transformed weight management, but they've also created chaos in the healthcare landscape. From med spa injections to proper medical supervision, this conversation sheds light on what safe GLP-1 treatment should actually loo...

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GLP-1 Medications Explained: The $200 Billion Healthcare Revolution | OON Episode 19

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In this episode of Out of Network, Dr. Ryon Parker and Dr. Rishi Seth dive deep into the explosive world of GLP-1 medications—exploring the realities of semaglutide, tirzepatide, Ozempic, Wegovy, and Zepbound. With a projected $200 billion market by...

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