GLP-1 Side Effects Explained: Why They Happen & How to Manage Them

In this episode of Health Recoded, we break down GLP-1 medication side effects, why they happen in the body, and how to manage them safely and effectively.GLP-1 receptor agonists (like semaglutide and tirzepatide) are increasingly used for weight loss, blood sugar control, and metabolic health—but many people experience side effects, especially during dose increases.In this episode, we cover:-How GLP-1 medications work in the body-Why side effects occur (and why they’re actually expected)-The most common side effects (nausea, bloating, slowed digestion, fatigue)-Less common but important side effects to be aware of-Why dose titration matters for tolerability-Practical, nurse-backed tips for managing side effectsIf you’re taking a GLP-1 medication—or considering one—this episode will help you better understand what your body is experiencing and how to support it.If this helped you understand your body a little better, consider subscribing for more evidence-based health conversations each week. New episodes weekly on health, metabolism, and nervous system education.Chapters00:00 Intro00:46 How GLP-1 Medications Work in the Body01:35 Why Side Effects Happen03:00 Common GLP-1 Side Effects14:44 Less Common but Important Side Effects17:53 Why Dose Titration Matters18:30 Key TakeawaysThis content is for educational and informational purposes only and is not a substitute for medical advice from your own healthcare provider.Resources:Cleveland Clinic – GLP-1 Agonists:https://my.clevelandclinic.org/health/treatments/13901-glp-1-agonistsNIH Review on GLP-1 Mechanisms:https://pmc.ncbi.nlm.nih.gov/articles/PMC5397288/Johns Hopkins – Managing GLP-1 Side Effects:https://www.hopkinsmd.com/blog/managing-glp-1-side-effects-our-top-tips-for-success