GLP-1s: Benefits, Risks, Muscle Loss & How to Do Them Safely episode artwork

EPISODE · Feb 15, 2026 · 20 MIN

GLP-1s: Benefits, Risks, Muscle Loss & How to Do Them Safely

from The Midlife Truth: Science-backed conversations on hormones, health, aesthetics, and aging well · host Lutricia Bennett

GLP 1 medications like Ozempic and Wegovy are powerful tools for weight loss, insulin resistance, PCOS, and metabolic health. But there is a side of the conversation most people are not talking about. Muscle loss.In this episode, I sit down with my partner and fellow Nurse Practitioner, Misty, to break down the truth about GLP 1 medications. We discuss how they work, why they help with insulin resistance and inflammation, and how improper use can lead to muscle loss, metabolic slowdown, and long term weight regain.With over 20 years of experience as nurse practitioners, we share how we use biometrics, protein goals based on fat free mass, strength training, and structured maintenance plans to protect muscle and support sustainable weight loss.If you are considering a GLP 1, currently taking one, or worried about regaining weight, this episode will give you clarity.00:00 Introduction and why GLP 1s are trending01:00 History of GLP 1 medications04:30 Benefits for diabetes, PCOS, inflammation and heart health06:30 The muscle loss and bone loss concern09:00 Protein goals and fat free mass explained11:30 Metabolism, starvation diets and hormone impact13:55 Maintenance plans after weight loss17:00 Strength training and insulin resistance20:00 Final thoughts and key takeaways

GLP 1 medications like Ozempic and Wegovy are powerful tools for weight loss, insulin resistance, PCOS, and metabolic health. But there is a side of the conversation most people are not talking about. Muscle loss. In this episode, I sit down with my partner and fellow Nurse Practitioner, Misty, to break down the truth about GLP 1 medications. We discuss how they work, why they help with insulin resistance and inflammation, and how improper use can lead to muscle loss, metabolic slowdown, and ...

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GLP-1s: Benefits, Risks, Muscle Loss & How to Do Them Safely

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This episode was published on February 15, 2026.

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GLP 1 medications like Ozempic and Wegovy are powerful tools for weight loss, insulin resistance, PCOS, and metabolic health. But there is a side of the conversation most people are not talking about. Muscle loss.In this episode, I sit down with my...

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