GLP-1s Explained: Benefits, Side Effects, Safety, and Real Expectations for Weight Loss Drugs episode artwork

EPISODE · Feb 11, 2026 · 44 MIN

GLP-1s Explained: Benefits, Side Effects, Safety, and Real Expectations for Weight Loss Drugs

from Co-Movement Gym Podcast · host Josh Lewis, Andy Cieply, and Dr. Ricky McDonough

GLP-1 medications like Ozempic and Wegovy are everywhere—and so are the opinions. In this episode, Andrew breaks down what GLP-1 actually is (a natural gut hormone), how GLP-1 medications work, and why newer “dual agonist” options like Mounjaro/Zepbound tend to produce bigger weight-loss results. We also tackle the controversy: is obesity a disease, and are GLP-1s “taking the easy way out”?You’ll hear a coach’s perspective from years in the trenches—why weight loss is effortless for some people and brutally hard for others, what typical results look like, common side effects, why many people stop, and what usually happens when you discontinue the meds.Chapters00:00 — Why GLP-1s are “big” right now01:12 — How common is obesity and GLP-1 use?05:20 — Obesity as a disease09:10 — The blame game12:40 — Are GLP-1's the easy way out?23:16 — GLP 101: what it is and what it does31:30 — Results, side-effects, and plateausThe Co-Movement Gym Podcast is supported by Native Path Supplements and Lombardi Chiropractic.🌱 Native Path Supplements: Use code COMO25 at checkout for 25% off any order at NativePath or pick up a bundle of our favorite products at a special price!44% off Native Hydrate: nativehydrate.com/comovement57% off Collagen Peptides: getnativepath.com/comovement41% off Complete Protein: nativepathcompleteprotein.com/comovement🩺 Lombardi Chiropractic: Mention the Co-Movement Gym Podcast when scheduling your initial appointment for 50% off Initial Consultation and X-Rays! https://www.lombardichiropractic.com/🏋️ Co-Movement Gym is a private movement facility in Oriskany Falls, NY offering Individualized Coaching, and Remote Programming to the best humans on the planet. We have worked with thousands of clients around the world for over 14 years and would love to create a personalized plan for you!Email: [email protected]: https://www.co-movement.com/Instagram: https://www.instagram.com/co_movementhqHashtags: #glp1 #ozempic #wegovy #mounjaro #zepbound #weightloss #obesity #metabolichealth #type2diabetes #insulinresistance #nutrition #protein #satiety #health #longevity #fitness

GLP-1 medications like Ozempic and Wegovy are everywhere—and so are the opinions. In this episode, Andrew breaks down what GLP-1 actually is (a natural gut hormone), how GLP-1 medications work, and why newer “dual agonist” options like Mounjaro/Zepbound tend to produce bigger weight-loss results. We also tackle the controversy: is obesity a disease, and are GLP-1s “taking the easy way out”? You’ll hear a coach’s perspective from years in the trenches—why weight loss is effortless for some peo...

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GLP-1s Explained: Benefits, Side Effects, Safety, and Real Expectations for Weight Loss Drugs

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This episode was published on February 11, 2026.

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GLP-1 medications like Ozempic and Wegovy are everywhere—and so are the opinions. In this episode, Andrew breaks down what GLP-1 actually is (a natural gut hormone), how GLP-1 medications work, and why newer “dual agonist” options like...

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