Glucocorticoids in the Setting of Active Infection

from Healio Rheuminations · host Adam J. Brown, MD

With COVID-19 and the question of whether glucocorticoids could be beneficial, this episode digs into the data on the use of glucocorticoids in the setting of infections, from pneumonia and septic arthritis, to meningitis and septic shock. Intro :11 In this episode :25 The first published case series of patients with serious infection 6:45 Otolaryngologic infections 7:43 Pneumonia, malaria and flu 8:26 Cortisone in strep throat 9:22 Major severe infections 11:26 A review article 12:12 Specific organ systems 13:25 Dexamethasone for bacterial meningitis 25:28 Septic shock 26:19 Dearth of data on glucocorticoids for influenza 32:10 Summary and take-home 35:19 Disclosure: Brown reports no relevant financial disclosures. We'd love to hear from you! Send your comments/questions to [email protected]. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum References: Annane D, et al. JAMA. 2002;288:862-871. Annane D, et al. N Engl J Med. 2018;378:809-818. Bennett IL, et al. JAMA. 1963;183:462-465. Blum CA, et al. Lancet. 2015;385:1511-1518. de Gans J, van de Beek D. N Engl J Med. 2002;347:1549-1556. Dellinger RP, et al. Crit Care Med. 2013;41:580-637. Fogel I, et al. Pediatrics. 2015;136:e776. Hahn EO, et al. J Clin Invest. 1951;30:274-281. Hartman FA, Merle Scott WJ. Proc Soc Exp Biol and Med. 1931;28:478-479. Hinshaw LB, et al. J Surg Res. 1980;28:151-170. Nedel WL, et al. World J Crit Care Med. 2016;5:89-95. Odio CM, et al. Pediatr Infect Dis J. 2003;22:883-888. Perla D, Marmorston J. Endocrinology. 1940;27:368-374. Stern A, et al. Cochrane Database Syst Rev. 2017;12:doi:10.1002/14651858.CD007720.pub3 Venkatesh B, et al. N Engl J Med. 2018;378:797-808. Wenner WF, Cone AJ. Arch Otolaryngol. 1934;20:178-187. Whitehead KW, Smith C. Proc Soc Expert Biol and Med. 1932;29:672-673. Wysenbeek AJ, et al. Ann Rheum Dis. 1998;57:687–690. Zhou Y, et al. Sci Rep. 2020;10:https://doi.org/10.1038/s41598-020-59732-7.

Episode metadata supplied by the publisher feed · Published Jun 22, 2020

Embed this episode

Attribution link and audio player

NOW PLAYING

Glucocorticoids in the Setting of Active Infection

0:00 35:57

1×

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

Share this episode

Similar Episodes

No similar episodes found.

Similar Podcasts

Unmasking COVID-19 Healio Information about COVID-19 is evolving at a rapid pace. To help physicians stay informed of the latest developments, infectious disease physician Gitanjali Pai MD, AAHIVS, will field questions from clinicians across numerous specialties about managing vulnerable patients during the COVID-19 pandemic. Oncology Overdrive Shikha Jain, MD In this podcast by Healio, host Shikha Jain, MD, FACP, covers modern day health care in an ever-evolving world. Through interviews with experts, Jain explores hot topics in oncology and beyond. Beneath the Surface Joel M. Gelfand, MD A Healio podcast hosted by Joel M. Gelfand, MD, discussing the latest news and hot topics in the field of dermatology. Gut Talk Sameer K. Berry, MD, and William D. Chey, MD Sameer K. Berry, MD, and William D. Chey, MD, host this Healio podcast that provides busy clinicians with quick updates that directly affect their GI practices. Through interviews and candid conversations, they explore how health policy, social media, technology, nutrition, practice management and research impact the field of Gastroenterology. Most importantly, the show also features interviews with patients to add a unique perspective on the topics that matter.

Frequently Asked Questions

How long is this episode of Healio Rheuminations?

This episode is 35 minutes long.

When was this Healio Rheuminations episode published?

This episode was published on June 22, 2020.

Can I download this Healio Rheuminations episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.

URL copied to clipboard!