EPISODE · Jun 2, 2025 · 4 MIN
Glutamate, Aspartate & Pyrimidine Synthesis
from Metabolism Made Easy · host A J Ghalayini, Ph.D.
This podcast covers the amino acid contribution to the synthesis of the pyrimidine ring. The podcast also covers the regulation of the rate-limiting enzyme of pyrimidine synthesis carbamoylphosphate synthase II (CPSII). It is inhibited by UTP and activated by ATP and PRPP. A comparison of CPS I and CPSII is also included.
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Glutamate, Aspartate & Pyrimidine Synthesis
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