Gluten, MTHFR, Mast Cells, and More | Office Hours (Ep 155) episode artwork

EPISODE · Jul 24, 2025 · 55 MIN

Gluten, MTHFR, Mast Cells, and More | Office Hours (Ep 155)

from Bendy Bodies with Dr. Linda Bluestein · host Dr. Linda Bluestein

In this solo episode of the Bendy Bodies Podcast, Dr. Linda Bluestein tackles a series of complex listener questions originally submitted by clinicians after her guest appearance on The Curbsiders internal medicine podcast. From the flaws in the EDS diagnostic criteria to the misunderstood role of MTHFR gene (methylenetetrahydrofolate reductase), SVT (supraventricular tachycardia), celiac disease, and mast cell medications, she offers guidance, clarity, and practical advice. She also digs into how to find a provider who actually understands dysautonomia and shares personal hacks that empower patients to ask smarter questions during appointments. This episode is a toolkit for patients and providers alike, packed with real-world insights you won’t want to miss. Takeaways: Why Beighton scoring alone doesn’t cut it for diagnosing EDS The truth about MTHFR variants and their link to EDS The overlap between SVT, POTS, and when to worry What to ask your doctor if you’re not sure they "get" dysautonomia A breakdown of meds like LDN, ketotifen, and cromolyn—and who they help most References: The Curbsiders Podcast EP 480 - Hypermobility with Dr. Linda Bluestein: https://thecurbsiders.com/curbsiders-podcast/480-hypermobility-with-dr-linda-bluestein https://pubmed.ncbi.nlm.nih.gov/38523329/?utm_source=chatgpt.com hEDS Diagnostic Criteria Checklist Red Flags Guide (credit: Clair A. Francomano, MD): https://www.bendybodiespodcast.com/p/redflags/ Hope for Hypermobility Article: https://www.nursingcenter.com/cearticle?an=00587875-202304000-00001&Journal_ID=3402523&Issue_ID=6649307 Substack: https://open.substack.com/pub/hypermobilitymd/p/navigating-treatment-for-hedshsd Find the episode transcript here Bendy Bodies EP 133: How Internists Think About Complex Illness with Dr. Matthew Watto: https://www.bendybodiespodcast.com/how-internists-think-about-complex-illness-with-dr-matthew-watto-ben-133/ Bendy Bodies EP 139: Hidden Histamine Threats with Dr. Theoharis Theoharides: https://www.bendybodiespodcast.com/hidden-histamine-threats-with-dr-theoharis-theoharides-ep-139/ Cromolyn Douche Article: https://pubmed.ncbi.nlm.nih.gov/30964355/ https://www.bendybodiespodcast.com/videos/connective-tissue-disorders-and-lipedema-with-karen-herbst-md/ LDN episode: https://www.bendybodiespodcast.com/lower-your-eds-pain-office-hours-ep-138/ LDN resource: https://www.bendybodiespodcast.com/p/low-dose-naltrexone-ldn-for-chronic-pain-eds/ Want more Dr. Linda Bluestein, MD? Website:  ⁠⁠https://www.hypermobilitymd.com/⁠⁠. YouTube: ⁠⁠⁠youtube.com/@bendybodiespodcast⁠⁠⁠  Instagram: ⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠  Facebook: ⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠  X: ⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠  LinkedIn: ⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠  Newsletter: ⁠⁠⁠https://hypermobilitymd.substack.com/⁠⁠⁠ Shop my Amazon store ⁠⁠⁠https://www.amazon.com/shop/hypermobilitymd⁠⁠⁠ Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority! Use this affiliate link for Algonot to get an extra 5% off your entire order: ⁠⁠https://algonot.com/coupon/bendbod/⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠[email protected]⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

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Gluten, MTHFR, Mast Cells, and More | Office Hours (Ep 155)

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