Glycans, Inflammation & Biological Age: A New Lens on Longevity

Find Nina Patrick here: https://qrco.de/bgXpKn----------Sponsor: GlycanAge Inflammaging drives CVD, metabolic disorders, and accelerated aging, but clinicians still lack reliable tools to measure, intervene, and track it in practice. GlycanAge brings together leading experts to close that gap with practical frameworks for assessing immune aging in real-world clinical settings.Register via the link below and join the one-day event to learn how to measure immune aging and apply it to preventive and longevity care.Date: June 20 2026 | Location: Hotel Dubrovnik Palace, CroatiaLink: https://glycanage.com/inflammaging-in-clinical-practice----------Guests: Nikolina LaucCEO & Co-Founder of GlycanAgeLinkedIn: https://www.linkedin.com/in/nikolinalauc/Website: https://glycanage.com/----------What if glycans—the neglected sugars on immune proteins—reveal inflammation and biological age more accurately than DNA methylation or CRP?Phil Newman and Dr. Nina Patrick sit down with Nikolina Lauc, CEO and co-founder of GlycanAge, to explore how these biomarkers integrate genetics, epigenetics, and environment for superior aging insights.Together they explain glycan shifts predicting cardiovascular events better than standard markers, with 300,000+ samples showing changes up to 10 years before diabetes. From perimenopause accelerating biological age by nine years (or decades in months for some) to moderate exercise yielding 10 years younger profiles versus pros matching sedentary inflammation, these reveal immune-driven aging realities. Contrasting epigenetic clocks' 10% variability (five-year swings same-day), glycans stay stable within one year.They also discuss hormone replacement reversing effects, fasting dropping profiles in days despite 21-day half-life, overtraining myths, and psychology like PTSD adding 15 years immune age—pushing immune resilience scores over raw age.In this episode, you’ll learn:Glycans predict CV risk/mortality across 350+ papers, outperforming CRPPerimenopause doubles aging rate; estrogen reverses 9-year spikeOver-exercisers match sedentary inflammation; moderates gain 10 yearsFasting alters glycans in days vs 21-day half-lifeStress/divorce adds decades; PTSD shortens expectancy 15-20 yearsGlycans enable modifiable risk scores for hospitals like NorthwesternIf you want to understand why inflammation may be the true driver of aging, this episode connects large-scale glycan data with real-world clinical implications for prevention and longevity.Subscribe for weekly episodes that explore longevity science, preventative medicine, and the systems shaping how we live longer and better.----------Hosts:Phil Newman: https://qrco.de/bgXpNYNina Patrick: ⁠⁠https://qrco.de/bgXpKn