Hacking DNA: What Anthropic's Mythos Model Means for Medicine

Anthropic just announced Claude Mythos Preview — an AI model so capable at finding software vulnerabilities that they won't release it publicly. Instead, they launched Project Glasswing with Apple, Google, Microsoft, and others, committing $100M to use the model defensively. In weeks, Mythos found thousands of zero-day vulnerabilities across every major operating system and browser — including one in OpenBSD hiding for 27 years.But the cybersecurity headlines aren't the whole story. The same vulnerability chaining capability that links multiple software flaws into sophisticated exploits maps directly to how polygenic disease works — cascading gene interactions across multiple variants that we've never been able to trace. With models like Arc Institute's Evo 2 and DeepMind's AlphaGenome already decoding the genome, Mythos-class reasoning could change everything about how we understand and treat disease.If we can hack code to break it, we can hack code to fix it — including the code that makes us sick.Sources and full write-up: https://open.substack.com/pub/danmccoymd/p/hacking-dna-the-anthropic-story-nobodys