HCPLive 5 Stories in Under 5: Week of 09/28

Welcome to HCPLive's 5 Stories in Under 5—your quick, must-know recap of the top 5 healthcare stories from the past week, all in under 5 minutes. Stay informed, stay ahead, and let’s dive into the latest updates impacting clinicians and healthcare providers like you!Interested in a more traditional, text rundown? Check out the HCPFive!Top 5 Healthcare Headlines for September 28-October 4, 2025:FDA Approves Guselkumab (Tremfya) for Pediatric Plaque Psoriasis, Psoriatic ArthritisThe FDA approved guselkumab as the first IL-23 inhibitor for children ≥6 years with moderate-to-severe plaque psoriasis or active psoriatic arthritis.FDA Approves Remibrutinib for Chronic Spontaneous UrticariaRemibrutinib, a selective BTK inhibitor, gained FDA approval for adults with chronic spontaneous urticaria based on sustained efficacy in phase 3 trials.Novo Nordisk Resubmits Insulin Icodec (Awiqli) Injection BLA for Type 2 DiabetesNovo Nordisk resubmitted its once-weekly insulin icodec BLA for type 2 diabetes after addressing prior FDA concerns.Novo Nordisk Submits Denecimig (Mim8) BLA for Hemophilia ANovo Nordisk filed a BLA for denecimig as prophylaxis for hemophilia A, supported by FRONTIER program data.VESALIUS-CV: Evolocumab (Repatha) Achieves Primary Endpoints in Patients with ASCVDEvolocumab reduced major cardiovascular events in ASCVD patients without prior MI or stroke in the phase 3 VESALIUS-CV trial.