HER2+ Metastatic Breast Cancer: Cleopatra, DESTINY-Breast09 & What Comes Next - Drs. Bill Gradishar, Tarah Ballinger, & Megan Kruse episode artwork

EPISODE · Jan 6, 2026 · 25 MIN

HER2+ Metastatic Breast Cancer: Cleopatra, DESTINY-Breast09 & What Comes Next - Drs. Bill Gradishar, Tarah Ballinger, & Megan Kruse

from Community Health Media · host Community Health Media

For more than a decade, the Cleopatra regimen transformed outcomes in HER2-positive metastatic breast cancer — delivering landmark overall survival gains and redefining long-term disease control.Recorded at SABCS, this expert roundtable features Dr. Bill Gradishar, Dr. Tarah Ballinger, and Dr. Megan Kruse as they examine how the HER2 landscape is evolving in the era of antibody–drug conjugates.The discussion explores the real-world impact of DESTINY-Breast09, the role of trastuzumab deruxtecan (T-DXd) in the first-line setting, and how clinicians are balancing efficacy, toxicity, and quality of life. From induction vs maintenance strategies to emerging data from PATINA and HER2CLIMB-05, this conversation highlights the nuance required in modern HER2+ decision-making.🎧 A must-watch conversation on progress, uncertainty, and shared decision-making in HER2-positive metastatic breast cancer.#HER2Positive #MetastaticBreastCancer #BreastCancer #Oncology #DESTINYBreast09 #TDXd #CleopatraTrial #AntibodyDrugConjugates #MedicalOncology #BreastOncology #SABCS #CommunityHealthMedia–Thanks for watching!Our podcasts are also available on: • Spotify - https://spotf.fi/chm-podcast • Amazon Music - https://amazn.so/chm-podcast • Apple Podcast - https://podcasts.apple.com/us/podcast/community-health-media/id1837428248 • Castbox - https://castbox.fm/vh/6735434 • Goodpods - https://goodpods.com/profile/chm-111066 • iHeartRadio - https://iheart.com/podcast/291542082 • Pocket Casts - https://pca.st/3ncdh11o–Community Health Media (CHM) is your full service healthcare communications partner, combining our production expertise with targeted multi-channel campaigns. We connect companies and healthcare brands with key opinion leaders, patients, and consumers through compelling content and live experiences.We’re an integrated marketing company that produces world-class content and curated peer to peer live experiences.We specialize in: • Peer to peer interviews, panels & round-tables • Curated live events & conferences • Professional in-depth content & research updates • Interactive learning modules & webinars • Live & on-demand webcasts & podcastsLearn more about us here - https://communityhealth.media

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HER2+ Metastatic Breast Cancer: Cleopatra, DESTINY-Breast09 & What Comes Next - Drs. Bill Gradishar, Tarah Ballinger, & Megan Kruse

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