Histamine Production by the Gut Microbiota Induces Visceral Hyperalgesia through Histamine 4 Receptor Signaling in Mice

Synopsys: Irritable bowel syndrome, or IBS, is a common disorder characterized by abdominal pain and altered bowel habits. While there may be multiple mechanisms that lead to development of IBS, the bacteria in our gut appear to play an important role in a number of IBS patients. We discuss novel research by scientists at Queen’s University […]