EPISODE · Jun 11, 2026 · 51 MIN
How A Vaccine Against Vascular Aging Could Prevent Heart Attacks and Stroke
from Own Your Heart Health with Dr. Regina Druz · host Dr. Regina Druz
What if the cells quietly destroying your blood vessels from the inside could be targeted, cleared, and replaced? Dr. David Scieszka, CEO of Vertical Longevity Pharma, joins Dr. Regina Druz to talk about a vaccine in development that targets senescent endothelial cells, the zombie cells that make blood vessels leaky, drive systemic inflammation, and sit at the center of the aging process itself. This is not another conversation about cholesterol or statins. It is about going upstream, to the vascular aging happening at the cellular level that most cardiovascular approaches never touch. In preclinical studies, clearing these senescent cells from the endothelium produced therapeutic benefits across every organ and system researchers were able to monitor. Heart function. Pulmonary function. Metabolic markers.The vaccine is designed to work by retraining the immune system to clear these cells the way it did at a younger age. Dr. Druz, author of the upcoming book Longevity Switches, connects this science to what she sees in her cardiology practice every day and what she believes is one of the most significant frontiers in cardiovascular health. If you want to understand where the science of aging and heart disease is actually heading, this episode is where to start. Episode Breakdown: 00:00 Senescent Cells and the Vaccine Targeting Atherosclerosis 03:17 From Military Psyops to Longevity Research 10:25 Why Aging Is Vascular 13:37 Zombie Cells and the Endothelium Explained 16:44 How the Vaccine Trains the Immune System 25:37 Organ Rejuvenation Results in Mouse Studies 31:42 Plaque Regression Data and What It Means 35:28 Preventing Atherosclerosis in High-Risk Patients 38:33 Metabolic Disease and Diabetes Markers 41:52 Future Indications and Global Access 44:35 Primate Studies and the Path to Human Trials Links: Schedule a Discovery Call Access Courses and Events Get Heartwell Toolkits Schedule a Business Meeting Connect with Dr. Regina Druz: Visit the Holistic Heart Centers website Follow Holistic Heart Centers on Facebook Follow Holistic Heart Centers on X Subscribe to Dr. Regina on YouTube Follow Dr. Regina on Instagram Follow Dr. Regina on TikTok Podcast production and show notes provided by HiveCast.fm
What this episode covers
What if the cells quietly destroying your blood vessels from the inside could be targeted, cleared, and replaced? Dr. David Scieszka, CEO of Vertical Longevity Pharma, joins Dr. Regina Druz to talk about a vaccine in development that targets senescent endothelial cells, the zombie cells that make blood vessels leaky, drive systemic inflammation, and sit at the center of the aging process itself. This is not another conversation about cholesterol or statins. It is about going upstream, to the vascular aging happening at the cellular level that most cardiovascular approaches never touch. In preclinical studies, clearing these senescent cells from the endothelium produced therapeutic benefits across every organ and system researchers were able to monitor. Heart function. Pulmonary function. Metabolic markers.The vaccine is designed to work by retraining the immune system to clear these cells the way it did at a younger age. Dr. Druz, author of the upcoming book Longevity Switches, connects this science to what she sees in her cardiology practice every day and what she believes is one of the most significant frontiers in cardiovascular health. If you want to understand where the science of aging and heart disease is actually heading, this episode is where to start. Episode Breakdown: 00:00 Senescent Cells and the Vaccine Targeting Atherosclerosis 03:17 From Military Psyops to Longevity Research 10:25 Why Aging Is Vascular 13:37 Zombie Cells and the Endothelium Explained 16:44 How the Vaccine Trains the Immune System 25:37 Organ Rejuvenation Results in Mouse Studies 31:42 Plaque Regression Data and What It Means 35:28 Preventing Atherosclerosis in High-Risk Patients 38:33 Metabolic Disease and Diabetes Markers 41:52 Future Indications and Global Access 44:35 Primate Studies and the Path to Human Trials Links: Schedule a Discovery Call Access Courses and Events Get Heartwell Toolkits Schedule a Business Meeting Connect with Dr. Regina Druz: Visit the Holistic Heart Centers website Follow Holistic Heart Centers on Facebook Follow Holistic Heart Centers on X Subscribe to Dr. Regina on YouTube Follow Dr. Regina on Instagram Follow Dr. Regina on TikTok Podcast production and show notes provided by HiveCast.fm
NOW PLAYING
How A Vaccine Against Vascular Aging Could Prevent Heart Attacks and Stroke
No transcript for this episode yet
Similar Episodes
Mar 26, 2026 ·1m
Mar 19, 2026 ·34m
Feb 18, 2026 ·11m
Feb 11, 2026 ·45m