How Ketamine Works on the Brain — An ER Doctor Explains (What Antidepressants Can't Do) episode artwork

EPISODE · Mar 26, 2026 · 5 MIN

How Ketamine Works on the Brain — An ER Doctor Explains (What Antidepressants Can't Do)

from Rewire & Thrive · host Dr. Dee Bonney

After 25 years as an ER physician, I've seen what happens when people are suffering and the standard treatments just don't work. In this video, I'm going to show you — on a whiteboard — exactly what's happening inside your brain when you're depressed, why antidepressants fail for so many people, and how ketamine does something no other treatment can.This isn't theory. At Alpha Omega Wellness, we've helped over 800 patients reduce their depression and anxiety scores by 65–70% in just 3–4 weeks. Here's the science behind why that's possible.What you'll learn:✔ Why your brain LOSES neural connections when you're depressed✔ Why antidepressants can't fix structural brain damage✔ What BDNF is — and why it's like Miracle-Gro for your brain✔ How ketamine grows new connections within hours✔ Who is and isn't a good candidateIf you or someone you love has tried antidepressants, therapy, and still isn't better — this podcast is for you.

Episode metadata supplied by the publisher feed · Published Mar 26, 2026

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After 25 years as an ER physician, I've seen what happens when people are suffering and the standard treatments just don't work. In this video, I'm going to show you — on a whiteboard — exactly what's happening inside your brain when you're depressed, why antidepressants fail for so many people, and how ketamine does something no other treatment can. This isn't theory. At Alpha Omega Wellness, we've helped over 800 patients reduce their depression and anxiety scores by 65–70% in just 3–4 w...

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How Ketamine Works on the Brain — An ER Doctor Explains (What Antidepressants Can't Do)

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