How The Gut Talks Your Brain Into Mood, Metabolism, And Longevity episode artwork

EPISODE · Nov 20, 2025 · 10 MIN

How The Gut Talks Your Brain Into Mood, Metabolism, And Longevity

from The Longevity Podcast: Optimizing HealthSpan & MindSpan · host Dung Trinh

Send us Fan MailWe map the gut brain axis from the enteric nervous system to the vagus nerve and the microbiome, then explain how short-chain fatty acids protect both gut and brain barriers. Dysbiosis emerges as a driver of inflammation, brain fog, and accelerated aging, with clear steps to shift the balance.• ENS as an autonomous neural network with 100 million neurons• Vagus nerve traffic flowing 90 percent from gut to brain• Microbiome roles in nutrient extraction, immune training, and neurotransmitters• Serotonin, dopamine, and GABA influence on mood and calm• SCFAs, especially butyrate, supporting gut and blood-brain barriers• Dysbiosis leading to leaky gut, systemic inflammation, and cognitive decline• Practical lens for longevity by reinforcing the gut brain axisThis podcast is created by Ai for educational and entertainment purposes only and does not constitute professional medical or health advice. Please talk to your healthcare team for medical advice. Never miss an episode—subscribe on your favorite podcast app!

Episode metadata supplied by the publisher feed · Published Nov 20, 2025

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Send us Fan Mail We map the gut brain axis from the enteric nervous system to the vagus nerve and the microbiome, then explain how short-chain fatty acids protect both gut and brain barriers. Dysbiosis emerges as a driver of inflammation, brain fog, and accelerated aging, with clear steps to shift the balance. • ENS as an autonomous neural network with 100 million neurons • Vagus nerve traffic flowing 90 percent from gut to brain • Microbiome roles in nutrient extraction, immune training, an...

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How The Gut Talks Your Brain Into Mood, Metabolism, And Longevity

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This episode was published on November 20, 2025.

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