EPISODE · Sep 15, 2026 · 9 MIN
How to Optimize Gluconeogenesis: Russell Clark's Clinical Approach
from CFP Weight Loss with Russell Clark · host Russell Clark, FNP-C
How to Optimize Gluconeogenesis: Russell Clark's Clinical Approach Welcome to CFP Weight Loss. I'm Russell Clark, Nurse Practitioner. Today, we're exploring How to Optimize Gluconeogenesis: Russell Clark's Clinical Approach. ... I'm not here to sensationalize. We'll examine the topic through research, physiology, and practical clinical experience. ... We'll touch on Gluconeogenesis, Tirzepatide Reset, Leptin Sensitivity — especially as they apply to real people over forty. ... Gluconeogenesis, the metabolic pathway that generates glucose from non-carbohydrate sources like amino acids, lactate, and glycerol, sits at the center of sustainable fat loss and metabolic health. Rather than fighting this ancient survival mechanism, clinician Russell Clark teaches patients to optimize it so the body efficiently produces just enough glucose while burning stored fat. His clinical framework moves beyond simplistic Calories In Calories Out models, focusing instead on hormonal orchestration, inflammation control, and mitochondrial performance. ... By strategically supporting gluconeogenesis, patients restore leptin sensitivity, lower HOMA-IR scores, and achieve lasting body composition improvements without perpetual medication dependence. Listen at CFP Weight Loss — clinical guide with Russell Clark, FNP-C. Read more: https://blog.cfpweightloss.com/bfly-optimize-gluconeogenesis
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