How to Program for Hypertrophy: Volume, Frequency & Exercise Selection (with Dr Eric Helms - Part 2) episode artwork

EPISODE · May 11, 2026 · 54 MIN

How to Program for Hypertrophy: Volume, Frequency & Exercise Selection (with Dr Eric Helms - Part 2)

from Stronger with Time · host Dr Tony Boutagy

Hypertrophy programming comes back to a few practical decisions: how close to failure, how much volume, how often, and how much variety.In this episode, I speak with Dr Eric Helms about how to make those decisions with better judgment, and where popular models claim more than the evidence supports.Dr Helms is a PhD researcher in strength and hypertrophy, a coach of physique and strength athletes, and a high-level natural bodybuilder.In Part 1, we discussed how to think about training advice when coaches, research, and physiology models do not point in the same direction. In this episode, we apply that thinking to programming.Some of what we discuss:How close to failure you actually need to train, and when it matters more or lessWhy “only the last 5 reps count” doesn’t hold upWhy estimating reps in reserve gets harder at higher repsHow much volume to use, and how frequency changes that decisionWhy fatigue matters, but may be overweighted in programming decisionsVariety vs variation, and why hypertrophy may not need strength-style periodisationWhere drop sets, rest-pause, and myo-reps actually fit, as time-saving tools rather than superior methodsWho this is for:Coaches programming hypertrophy for general population or athletes, and experienced lifters trying to make defensible decisions about failure, volume, frequency, and exercise selection without chasing every new trend.Guest and ResourcesDr Eric Helms3D Muscle Journey: https://www.3dmusclejourney.com/about/The Muscle and Strength Pyramids: https://muscleandstrengthpyramids.com/Research profile: https://www.researchgate.net/profile/Eric-Helms-2MASS Research Review: https://massresearchreview.com/about-us-2/Host: Dr Tony BoutagyExercise scientist and coach translating exercise science into practical training and programming decisions.Instagram: @tonyboutagyCourses, seminars, and resources: https://tonyboutagy.com/

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