How to Repair Your Skin Barrier: Hydration That Works + Fish Oil vs Astaxanthin (Lily Shapiro, PharmD)

If your skin still feels dry, reactive, or “stressed” even though you’re doing all the right things—this episode will bring the clarity you’ve been missing. I’m joined by Lily Shapiro, PharmD—a pharmacist and founder of ATIKA—who’s built a reputation for translating the science of skin aging, barrier biology, oxidative stress, and skin nutrition into practical guidance that actually works in real life. Lily doesn’t just talk trends; she explains the why behind what your skin is doing and what to change so you can see results. In our conversation, Lily breaks down what hydration truly means: it’s not just adding water—it’s strengthening your skin barrier so your skin can hold moisture. We also talk about how “over-optimizing” (sauna, red light, stacking too many protocols) can quietly backfire, and what a smarter, more sustainable approach looks like if your goal is calm, resilient, glowing skin. Then we go into one of my favorite questions: if you could take one supplement for life, what would it be? Lily explains why it comes down to fish oil vs astaxanthin, what each supports, and how to think about choosing the right one for your skin and longevity goals. In this episode, you’ll learn: The biggest misconceptions about hydration and why barrier health comes first How to tell if your routine is helping your skin—or stressing it out Why skin longevity is an “inside-out” conversation (not just topical products) Fish oil vs astaxanthin: what to consider before you choose Simple priorities that support stronger, more hydrated, more resilient skin Hosted by Danielle Keasling on Another Million Miles Podcast.