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EPISODE · May 8, 2026 · 4 MIN

How Your Weight Impacts Your Health

from Weight and Metabolism · host Dr Deepti Sharma, MD

Let's talk about what obesity actually does to your body — not to shame or scare you, but so you understand what's really at stake.In this episode, I walk through the hard science: obesity is an independent risk factor for sudden and premature death. All-cause mortality increases progressively with higher BMI, especially once you cross a BMI of 30. In the U.S. alone, obesity contributes to an estimated 300,000 deaths annually. For those with severe obesity (BMI over 40), life expectancy can be reduced by 5 to 20 years.But it's not just about lifespan — it's about how you live those years. Obesity affects every single organ system and is a central driver in the development of chronic diseases and 13 different types of cancer.We cover it all:Cardiovascular disease: hypertension, coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral vascular diseaseMetabolic disorders: type 2 diabetes, dyslipidemia, metabolic syndromeRespiratory issues: asthma, sleep apnea, hypoventilation syndromeGastrointestinal & liver disease: gallstones, reflux, IBS, fatty liver diseaseMusculoskeletal problems: osteoarthritis, chronic pain, mobility issues, increased fall riskCancer: 13 confirmed obesity-related cancers, including colorectal, breast, endometrial, pancreatic, and moreReproductive health: fertility issues, PCOS, erectile dysfunction, pregnancy complicationsMental health: depression, anxiety, body image struggles, stigma, and discrimination in healthcareThis episode isn't meant to overwhelm you. It's meant to help you see why addressing obesity isn't about vanity — it's about protecting your health, your quality of life, and your future.🌐 Learn more at weightandmetabolism.com

Episode metadata supplied by the publisher feed · Published May 8, 2026

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