HPI in the OR: Prediction Without Prevention?

In this episode of Updates in Anesthesiology, Dr. Hadzic unpacks a major 2025 multicenter trial by Dr. Javier Ripollés-Melchor and colleagues, exploring whether the Hypotension Prediction Index (HPI) can actually reduce postoperative acute kidney injury (AKI) in abdominal surgery. Despite HPI’s promise in predicting intraoperative hypotension, the trial found no reduction in AKI or overall complications compared to standard care. We break down what this means for your practice, how vasopressor choice might matter more than prediction tools, and why clinical judgment still reigns supreme in the OR. Stay tuned for the key takeaways and what to do with that HPI alert next time it flashes on your monitor.Where else to find us: Web- ⁠⁠http://www.nysora.com⁠⁠ Instagram- ⁠⁠instagram.com/nysora.inc/ ⁠⁠LinkedIN- ⁠⁠linkedin.com/company/nysora-inc/⁠⁠ Facebook- ⁠⁠facebook.com/nysora⁠⁠ Twitter- ⁠⁠x.com/nysora⁠⁠ TikTok- ⁠⁠tiktok.com/@nysora_inc⁠⁠ --------------------------------------------------------- ⁠⁠#nysora⁠⁠ ⁠⁠#regionalanesthesia⁠⁠ ⁠⁠#anesthesia⁠⁠Disclaimer: Medicine is an ever-changing science. As new research and clinical experience broaden, changes in treatment and drug therapy are required. The authors and publishers have checked with sources believed to be reliable in efforts to provide accurate information within the available or accepted standards of care. However, given the possibility of human error or changes in medical practice, neither the authors nor the publisher, nor any other party involved in the preparation of this platform warrants that the information contained herein is in every aspect accurate or complete, and they disclaim all responsibility for any errors or omissions for the results obtained from the use of the information contained in this work. Readers are advised to confirm the information contained herein with other sources. For example, readers are advised to check the product information of each drug mentioned, and that any information contained on NYSORA's Podcast is accurate.