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IBDP2: Melissa Snyder, Ph.D.

Melissa Snyder, Ph.D., discusses Mayo Clinic Laboratories’ serological evaluation for inflammatory bowel disease, which can help clarify disease presence in a small subset of patients for whom diagnosis using pathologic or imaging studies is unclear. Our

Episode 140 of the Answers from the Lab podcast, hosted by Mayo Clinic Laboratories, titled "IBDP2: Melissa Snyder, Ph.D." was published on April 19, 2022 and runs 20 minutes.

April 19, 2022 ·20m · Answers from the Lab

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Melissa Snyder, Ph.D., discusses Mayo Clinic Laboratories’ serological evaluation for inflammatory bowel disease, which can help clarify disease presence in a small subset of patients for whom diagnosis using pathologic or imaging studies is unclear. Our assay detects for the presence of specific antimicrobials and autoantibodies, which can help distinguish ulcerative colitis from Crohn’s disease.

(00:32)

Can you tell us a little bit about yourself, your background and your role here at Mayo Clinic?


(01:43)

Can you tell us a little bit about the test and also explain why it was unavailable for a period of time?


(05:46):

I know there must have been a lot of effort and a lot of time put in ensuring that even if it means taking the down and maybe even for financial loss for the Mayo clinic that we get it right.


(06:47):

From what I understand, as I understand it, it's more of an adjunct or a confirmative test that's used. Can you please expand a little bit on that?


(10:18):

Do they always have this done after calprotectin testing, or are they ordered at the same time, in some cases, is there ever a time when you would order both together or is it always one first and then the other?


(11:55):

You just mentioned some of the details behind the results, but some of the studies around the markers used in this test have shown some interesting data around the results being more highly predictive in determining Crohn's disease or ulcerative colitis in pediatric patients. Is that something you're familiar with?


(14:03):

And how does the Mayo Clinic test compare in efficiency or cost?


(17:34):

So we've Discussed quite a bit of information. How does all of this play into patient care?


(18:24):

Is anything else you'd like to add to those who may be considering ordering the IBD P two test through Mayo clinic laboratories, or maybe did in the past, but have switched labs and are still on the fence about coming back to MC for this test?

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