IBS news flash. IBS pain might be treated by targeting touch receptor episode artwork

EPISODE · Mar 12, 2025 · 1 MIN

IBS news flash. IBS pain might be treated by targeting touch receptor

from Heather's IBS Newsletter - Help for Irritable Bowel Syndrome. · host Heather Van Vorous

IBS news flash. IBS pain might be treated by targeting touch receptorA receptor responsible for your sense of touch and temperature could provide a target for treating IBS pain.A provocative study suggests that pain due to gut disorders - like IBS - might be treated by targeting a touch receptor.A receptor that is responsible for our sense of touch and temperature, and which researchers just found present in the colon, could provide a target for treating chronic pain associated with gut disorders - including IBS.Researchers have identified the presence of Piezo2, a receptor that is responsible for sensing light touch on your skin.Brace yourself.It was discovered that ”Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity.”In plain English?Since this receptor is in our guts, there’s the potential that selectively targeting these receptor channels could be used for long-term silencing of pain sensations from internal organs.As the study authors note: “Mechanisms underlying visceral pain are poorly understood, and the resulting lack of effective clinical management represents a major unmet medical problem.”No kidding!And more help for IBS pain.You are not alone.Heather's IBS Newsletter can’t continue without your support. Please become a paid subscriber.P.S. If you have any questions or comments I'd love to hear them - just reply to this email to reach me directly. I am overwhelmed with emails but I try to answer everyone. If you need immediate help please join my private IBS coaching.XOXOHeatherHeather Van Vorous Over 40 years dealing with IBSGet full help for IBS here Get full access to Heather's IBS Newsletter - Help for Irritable Bowel Syndrome at heathervanvorous.substack.com/subscribe

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