Impact of combined oral contraceptives and progestin-only pills on psychological and sexual well-being of women with endometriosis: A systematic review

Concerns persist that combined oral contraceptives or progestin-only pills may negatively affect psychological well-being or sexual function in endometriosis. Current evidence indicates these agents do not meaningfully worsen psychological or sexual outcomes and are generally well tolerated when pain improves.Noemi Salmeri, Martina Piccini, Francesca Caprara, Edgardo Somigliana, Paola Viganò, Paolo VercelliniFirst published: 12 March 2026 https://doi.org/10.1111/aogs.70183https://obgyn.onlinelibrary.wiley.com/toc/16000412/0/0