Infusing complexity with care: Brilliant Clinical Trial Expert, Helen McNaught reminds us that support is always the magic ingredient for patients

‘Novo Nordisk has not had any input into the development of the podcasts or the selection of speakers. Novo Nordisk is the sole sponsor of the activity’.Helen McNaught, a specialist trial nurse with a rich background in clinical research, shares her journey and insights in the latest edition of PEP Talks, a podcast by the International Society for Patient Engagement Professionals. Sponsored by Novo Nordisk, the episode delves into Helen's career, which began with a personal connection to clinical trials when her brother participated in a lifesaving trial for acute lymphoblastic leukaemia. Her professional path led her to specialise in haematology oncology at Cambridge University Hospital, where she worked on phase one to phase four clinical studies. Helen also contributed to Blood Cancer UK by starting a clinical trials navigation service, highlighting the need for better patient information and support.The podcast discusses the challenges and triumphs of patient engagement in clinical trials, emphasising the importance of practical considerations in trial design and the evolving role of patient advisory councils. Helen recounts a poignant story of a patient named Sue, who faced logistical challenges during a clinical trial, underscoring the need for more patient-centric approaches. Helen expresses optimism about the industry's shift towards meaningful patient engagement, noting the increasing receptiveness of pharma companies to patient input and the strategic integration of patient voices in trial design. The episode concludes with a call to action for more diverse perspectives in patient engagement, including insights from regulators and trial managers.