Inside the ZyMōt Chip: How Microfluidics Picks Better Sperm episode artwork

EPISODE · Sep 10, 2025 · 12 MIN

Inside the ZyMōt Chip: How Microfluidics Picks Better Sperm

from Taco Bout Fertility Tuesday · host Mark Amols, MD

Send us Fan MailIn this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols takes a deep dive into the ZyMōt microfluidic sperm chip — a device designed to mimic nature’s way of selecting the healthiest sperm.We explore:Why sperm DNA fragmentation matters for fertilization, embryo quality, and miscarriage risk.How the ZyMōt chip works compared to traditional methods like swim-up and density gradient centrifugation.What the science really shows — from lab data to clinical trials — including studies where the chip nearly doubled live birth rates in male-factor infertility, and others where it made little difference in unselected IVF populations.Which patients benefit the most: men with high DNA fragmentation, couples with male-factor infertility, and those with failed fertilization or poor embryos in past cycles.Practical considerations — cost, limitations, and why some clinics use it for everyone while others use it selectively.Is it a true game changer, or just another lab gadget? Tune in to find out.Thanks for tuning in to another episode of 'Taco Bout Fertility Tuesday' with Dr. Mark Amols. If you found this episode insightful, please share it with friends and family who might benefit from our discussion. Remember, your feedback is invaluable to us – leave us a review on Apple Podcasts, Spotify, or your preferred listening platform.Stay connected with us for updates and fertility tips – follow us on Facebook. For more resources and information, visit our website at www.NewDirectionFertility.com.Have a question or a topic you'd like us to cover? We'd love to hear from you! Reach out to us at [email protected] us next Tuesday for more discussions on fertility, where we blend medical expertise with a touch of humor to make complex topics accessible and engaging. Until then, keep the conversation going and remember: understanding your fertility is a journey we're on together.

Episode metadata supplied by the publisher feed · Published Sep 10, 2025

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Send us Fan Mail In this episode of Taco Bout Fertility Tuesday, Dr. Mark Amols takes a deep dive into the ZyMōt microfluidic sperm chip — a device designed to mimic nature’s way of selecting the healthiest sperm. We explore: Why sperm DNA fragmentation matters for fertilization, embryo quality, and miscarriage risk.How the ZyMōt chip works compared to traditional methods like swim-up and density gradient centrifugation.What the science really shows — from lab data to clinical trials — includ...

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Inside the ZyMōt Chip: How Microfluidics Picks Better Sperm

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This episode was published on September 10, 2025.

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