Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin episode artwork

EPISODE · Dec 23, 2025 · 2H 8M

Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin

from Dostcast · host Vinamre Kasanaa

Subscribe to Dostcast Clips:https://www.youtube.com/@dostcastclips?sub_confirmation=1Listen to Dostcast on Spotify: https://open.spotify.com/show/70vrbHeSvrcXyOeISTyBSy?si=be05dbdd564245d9Join the Dostcast Janta Party on WhatsApp for regular updates: https://whatsapp.com/channel/0029VbAZwo5D8SDs5kf94N3TWant to suggest a guest?Fill this form: https://docs.google.com/forms/d/1ft_-1QDs7XpsSWnaPOeF21yUlhk9bzKvwHSyh4hHfBU/edit?usp=drivesdk====================================================================Karan Sarin is a certified metabolic health coach, a two-time startup founder, and the author of Sick Nation. He specializes in decoding the root causes of metabolic dysfunction through the lenses of history, epigenetics, and modern physiology.In this episode, Vinamre and Karan discuss:The historical and epigenetic roots of fat gain and insulin resistanceThe science behind GLP-1 medications like Mounjaro and how they workCritical but overlooked clinical markers for diabetesWhy South Asians face unique metabolic challengesPractical steps to improve insulin sensitivity and long-term healthFollow Karan Sarin:Instagram: https://www.instagram.com/sweetreactions/?hl=enTimestamps 0:00 Coming Up1:10 History of Famine & Health13:54 Science Behind Fat Gain17:16 Are Our Genes Inferior?21:09 Are Medicines Flawed?27:47 Insulin Resistance & GLP-136:09 Insulin & Blood Sugar51:59 Undiagnosed Diabetic People54:49 Clinical Markers for Diabetes1:22:19 South Asians & Myostatins1:24:09 What’s the Cure?1:30:09 Nutrition1:37:59 Lifestyle Changes1:43:59 Mounjaro Experience1:45:09 Fats Have a Branding Problem1:54:09 Understanding & Handling Cortisol2:02:39 Conclusion====================================================================Vinamre Kasanaa is a writer at heart, podcaster and entrepreneur by craft.He spends a significant part of his time reading and researching.With over 500 podcasts under his belt, he’s interviewed everyone—from HNIs and industry leaders to everyday superheroes.Follow Vinamre:LinkedIn: https://www.linkedin.com/in/vinamre-kasanaa-b8524496/Instagram: https://www.instagram.com/vinamrekasanaa/Twitter: https://twitter.com/VinamreKasanaaDostcast: Instagram: https://www.instagram.com/dostcast/Twitter: https://twitter.com/dostcast====================================================================Contact Us:For business inquiries: [email protected]

Subscribe to Dostcast Clips:https://www.youtube.com/@dostcastclips?sub_confirmation=1Listen to Dostcast on Spotify: https://open.spotify.com/show/70vrbHeSvrcXyOeISTyBSy?si=be05dbdd564245d9Join the Dostcast Janta Party on WhatsApp for regular updates: https://whatsapp.com/channel/0029VbAZwo5D8SDs5kf94N3TWant to suggest a guest?Fill this form: https://docs.google.com/forms/d/1ft_-1QDs7XpsSWnaPOeF21yUlhk9bzKvwHSyh4hHfBU/edit?usp=drivesdk====================================================================Karan Sarin is a certified metabolic health coach, a two-time startup founder, and the author of Sick Nation. He specializes in decoding the root causes of metabolic dysfunction through the lenses of history, epigenetics, and modern physiology.In this episode, Vinamre and Karan discuss:The historical and epigenetic roots of fat gain and insulin resistanceThe science behind GLP-1 medications like Mounjaro and how they workCritical but overlooked clinical markers for diabetesWhy South Asians face unique metabolic challengesPractical steps to improve insulin sensitivity and long-term healthFollow Karan Sarin:Instagram: https://www.instagram.com/sweetreactions/?hl=enTimestamps 0:00 Coming Up1:10 History of Famine & Health13:54 Science Behind Fat Gain17:16 Are Our Genes Inferior?21:09 Are Medicines Flawed?27:47 Insulin Resistance & GLP-136:09 Insulin & Blood Sugar51:59 Undiagnosed Diabetic People54:49 Clinical Markers for Diabetes1:22:19 South Asians & Myostatins1:24:09 What’s the Cure?1:30:09 Nutrition1:37:59 Lifestyle Changes1:43:59 Mounjaro Experience1:45:09 Fats Have a Branding Problem1:54:09 Understanding & Handling Cortisol2:02:39 Conclusion====================================================================Vinamre Kasanaa is a writer at heart, podcaster and entrepreneur by craft.He spends a significant part of his time reading and researching.With over 500 podcasts under his belt, he’s interviewed everyone—from HNIs and industry leaders to everyday superheroes.Follow Vinamre:LinkedIn: https://www.linkedin.com/in/vinamre-kasanaa-b8524496/Instagram: https://www.instagram.com/vinamrekasanaa/Twitter: https://twitter.com/VinamreKasanaaDostcast: Instagram: https://www.instagram.com/dostcast/Twitter: https://twitter.com/dostcast====================================================================Contact Us:For business inquiries: [email protected]

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Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin

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