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Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin episode artwork

EPISODE · Dec 23, 2025 · 2H 8M

Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin

from Dostcast · host Vinamre Kasanaa

Subscribe to Dostcast Clips: https://www.youtube.com/@dostcastclips?sub_confirmation=1 Listen to Dostcast on Spotify: https://open.spotify.com/show/70vrbHeSvrcXyOeISTyBSy?si=be05dbdd564245d9 Join the Dostcast Janta Party on WhatsApp for regular updates: https://whatsapp.com/channel/0029VbAZwo5D8SDs5kf94N3T Want to suggest a guest? Fill this form: https://docs.google.com/forms/d/1ft_-1QDs7XpsSWnaPOeF21yUlhk9bzKvwHSyh4hHfBU/edit?usp=drivesdk ==================================================================== Karan Sarin is a certified metabolic health coach, a two-time startup founder, and the author of Sick Nation. He specializes in decoding the root causes of metabolic dysfunction through the lenses of history, epigenetics, and modern physiology. In this episode, Vinamre and Karan discuss: The historical and epigenetic roots of fat gain and insulin resistance The science behind GLP-1 medications like Mounjaro and how they work Critical but overlooked clinical markers for diabetes Why South Asians face unique metabolic challenges Practical steps to improve insulin sensitivity and long-term health Follow Karan Sarin: Instagram: https://www.instagram.com/sweetreactions/?hl=en Timestamps 0:00 Coming Up 1:10 History of Famine & Health 13:54 Science Behind Fat Gain 17:16 Are Our Genes Inferior? 21:09 Are Medicines Flawed? 27:47 Insulin Resistance & GLP-1 36:09 Insulin & Blood Sugar 51:59 Undiagnosed Diabetic People 54:49 Clinical Markers for Diabetes 1:22:19 South Asians & Myostatins 1:24:09 What’s the Cure? 1:30:09 Nutrition 1:37:59 Lifestyle Changes 1:43:59 Mounjaro Experience 1:45:09 Fats Have a Branding Problem 1:54:09 Understanding & Handling Cortisol 2:02:39 Conclusion ==================================================================== Vinamre Kasanaa is a writer at heart, podcaster and entrepreneur by craft. He spends a significant part of his time reading and researching. With over 500 podcasts under his belt, he’s interviewed everyone—from HNIs and industry leaders to everyday superheroes. Follow Vinamre: LinkedIn: https://www.linkedin.com/in/vinamre-kasanaa-b8524496/ Instagram: https://www.instagram.com/vinamrekasanaa/ Twitter: https://twitter.com/VinamreKasanaa Dostcast: Instagram: https://www.instagram.com/dostcast/ Twitter: https://twitter.com/dostcast ==================================================================== Contact Us: For business inquiries: [email protected]

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Insulin Expert on Insulin Resistance, Epigenetics, and Why India is a "Sick Nation" | Karan Sarin

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