Investigating the ubiquitin proteasome system

In today’s podcast Professor Selina Wray from University College London, meets four early career researchers, who know a great deal about the brain, human iPSC derived cells and the ubiquitin-proteasome pathway (not that isn’t a new type of electric car).We’ll be discussing their research, discovering more about super resolution microscopy, and how they’re researching the ubiquitin proteasome system, and its connection to dementia.We’re delighted to welcome our guests:PhD Students Liina Sirvio, Katiuska Daniela Pulgar Prieto from the UK Dementia Research Institute at Imperial College London. Georgie Lines, PhD Student from University College London and Dr Emma Mee Hayes a Postdoctoral Research Associate also from the UK Dementia Research Institute at Imperial College London.What is the purpose of ubiquitin proteasome system?In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development.--A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.Leave us a tip:https://dementia-researcher.captivate.fm/supportFollow us on social media:https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/https://www.twitter.com/demrescommunityhttps://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.socialDownload and Register with our Community App:https://www.onelink.to/dementiaresearcherWe gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.Subscribe to our sister show 'Dementia Researcher The Blogs':https://podfollow.com/dementia-researcher-blogs