Is it Possible to be Healthy and Obese? | Nick Sterling, M.D., Ph.D. #3

Is it possible to be metabolically healthy and overweight or obese? In this episode, we discuss the science of what makes fat healthy or unhealthy. We discuss how metabolic dysfunction in fat tissue can affect the rest of the body. We also review evidence pertaining to the "obesity paradox" and explore explanations for the associations of body mass index (BMI) and changes in the risk of disease complications and mortality. We discuss how metrics of central obesity can be used to obtain a better picture of an individual's metabolic health. Lastly, we discuss the critical link between exercise capacity and future health, as well as how to begin to transform our existing fat stores into a healthier state. Chapters: 00:00 - Introduction 00:50 - Healthy Obesity as an Idea 02:36 - Concepts of Healthy vs. Unhealthy Fat 02:59 - Subcutaneous, Visceral, and Ectopic Fat 05:22 - Adipocyte Hypertrophy 06:36 - Fat Cell Insulin Resistance 08:19 - The Obesity Paradox 12:23 - BMI & Age 13:53 - Bariatric Surgery 15:51 - Limitations of BMI 16:26 - Lifetime Maximal BMI 16:37 - Metrics of Central Adiposity 18:30 - Metabolically Healthy Obesity 21:38 - Exercise & Metabolically Healthy Obesity 22:36 - Improving the Health of Fat 24:03 - Exercise Capacity & Risk of Death 25:29 - Zone 2 Training 26:51 - The Effects of Weight Loss (Fat Loss) 27:55 - Summary Social & Website: Instagram - https://www.instagram.com/sterlingmdphd  Twitter - https://twitter.com/sterlingmdphd Facebook - https://www.facebook.com/sterlingmdphd TikTok - https://www.tiktok.com/@sterlingmdphd Newsletter - http://eepurl.com/hQpdqT Subscribe to the Podcast: Apple Podcasts: https://apple.co/3y438C9 Spotify: https://spoti.fi/3mZDvMv Google Podcasts: https://bit.ly/3Olanei References & Show Notes: http://www.nicksterling.com/ Maffetone Method: https://philmaffetone.com/180-formula/