Is open source AI really ahead of the frontier? 3 builders weigh in. | E25 episode artwork

EPISODE · Aug 6, 2026 · 1H 20M

Is open source AI really ahead of the frontier? 3 builders weigh in. | E25

from This Week in AI · host Jason Calacanis

This Week In Startups is made possible by:PAYPAL OPENToday’s show:China’s Alibaba just dropped a 2.4 trillion parameter open weight model that the company claims only trails Anthropic’s flagship among the major frontier rivals. Of course, this happened the very same week that the US government appears to have backed off from banning these models stateside entirely.Are these models anywhere close to actually catching up to the latest and greatest releases from US labs like Anthropic and OpenAI? Really seems to depend on who you ask. (Even long time friends JCal and Elon Musk can’t see eye to eye on it.)So on TWiAI Ep 25, we welcomed on Poolside AI CTO Eiso Kant, EXO Labs co-founder Alex Cheema, and Qloo founder Alex Elias to break down just how close Chinese labs are to catching up with the biggest and best models… and how long it will take US open weight builders to catch up.PLUS we explore the cutting edge of AI-powered baby sleep monitors, consider Hank Green’s public AI apology, and dig into sci-fi author Ursula K. LeGuin’s “hand-mind” thesis.Guests:Eiso Kant on X: https://x.com/eisokantPoolside: https://poolside.ai/Alex Elias on X: https://x.com/apeQloo: https://www.qloo.com/Alex Cheema on X: https://x.com/alexocheemaEXO Labs: https://exolabs.net/Local AI benchmark platform: https://local.ai/Relevant LinksQwen3.8-Max launch announcement: https://qwen.ai/blog?id=qwen3.8Bloomberg on Qwen3.8-Max launch: https://www.bloomberg.com/news/articles/2026-08-03/alibaba-drops-another-china-ai-model-with-breakthrough-performanceNYT: “White House Whipsaws Silicon Valley Over AI Rules”: https://www.nytimes.com/2026/08/04/technology/ai-washington-regulation-whiplash.htmlNvidia: “Open Weights and American AI Leadership”: https://images.nvidia.com/pdf/Open-Weights-and-American-AI-Leadership.pdfWorld Bank: World Development Report 2026: https://thedocs.worldbank.org/en/doc/1e4e52502104a331fb42cba0d4afa995-0050062026/original/WDR2026-Concept-Note.pdfHank Green apology on Reddit: https://www.reddit.com/r/nerdfighters/comments/1vbmoj5/comment/p0vzmog/Taylor Lorenz responds to Hank Green on X: https://x.com/TaylorLorenz/status/2083272682188206564TechCrunch: Substack partners with Pangram: https://techcrunch.com/2026/07/22/substacks-new-tool-tells-you-whos-been-writing-their-newsletters-with-ai/Amazon: Ursula K. Le Guin’s “Always Coming Home” expanded edition: https://www.amazon.com/Ursula-K-Guin-Authors-Expanded/dp/1598536036Timestamps:0:00 Guest intros and open10:03 Why Poolside thinks coding is the path to AGI12:55 A first look at EXO's local.ai16:24 The White House's open source pivot20:21 Margins, compute, and "dirt to intelligence"36:02 Jason's self-driving auction pitch37:58 Hank Green's AI apology38:45 Is AI addictive?1:08:31 What does it mean for AI to be "privacy first"?1:10:29 Enterprise AI sovereignty and "colonization"Sign up for the TWiAI newsletter!Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisCheck out all our partner offers: https://partners.launch.co/Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com

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Is open source AI really ahead of the frontier? 3 builders weigh in. | E25

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