Is There a Pill for BPD?  episode artwork

EPISODE · Oct 24, 2025 · 38 MIN

Is There a Pill for BPD?

from BPD Diaries: Stories and Science · host Stephanie Schildknecht

Medication and BPD: it’s one of the most debated, confusing, and personal topics out there. In this episode, we unpack what the research actually says about meds for BPD and what they can and can’t do.From antidepressants to mood stabilizers to the “medication merry-go-round,” we explore the science, the side effects, and our own lived experiences. Whether meds changed your life, didn’t help at all, or left you somewhere in between, this one’s for you.Trigger Warning: This episode contains frank discussion of medication, mental health treatment, and sensitive topics. Listener discretion is advised.🌱 Have questions, stories, or something you’d like us to cover? We’d love to hear from you. Email us at [email protected]⁠⁠⁠⁠⁠ and let’s keep the conversation going.🎧 Looking for meditations made for emotional regulation, BPD, and more? Check out  Empowered Heroes Meditations  on ⁠⁠⁠⁠Spotify.If you’d like more support in your journey toward BPD recovery, Steff offers 1:1 sessions using evidence-based tools from DBT and Mindfulness to help you heal. Email for a free 30-Minute Consultation: 📩 [email protected] or check out the website: www.bpdsupport.org📚 Referenced Research Includes:Bohus, M., Haaf, B., Simms, T., Limberger, M. F., Schmahl, C., Unckel, C., ... & Linehan, M. M. (2004). Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: a controlled trial. Behaviour research and therapy, 42(5), 487-499. https://doi.org/10.1016/S0005-7967(03)00174-8Crawford, M. J., Sanatinia, R., Barrett, B., Cunningham, G., Dale, O., Ganguli, P., ... & Reilly, J. G. (2018). Lamotrigine for people with borderline personality disorder: a RCT. Health Technology Assessment (Winchester, England), 22(17), 1.doi: 10.3310/hta22170Ingenhoven, T., Lafay, P., Rinne, T., Passchier, J., & Duivenvoorden, H. (2010). Effectiveness of pharmacotherapy for severe personality disorders: meta-analyses of randomized controlled trials. J Clin Psychiatry, 71(1), 14-25. 10.4088/JCP.08r04526greLieb, K., Völlm, B., Rücker, G., Timmer, A., & Stoffers, J. M. (2010). Pharmacotherapy for borderline personality disorder: Cochrane systematic review of randomised trials. The British Journal of Psychiatry, 196(1), 4-12. doi:10.1192/bjp.bp.108.062984National Institute for Health and Care Excellence (NICE). (2009). Borderline personality disorder: recognition and management. Clinical guideline [CG78]. https://www.nice.org.uk/guidance/cg78Ripoll, L. H. (2012). Clinical psychopharmacology of borderline personality disorder: an update on the available evidence in light of the Diagnostic and Statistical Manual of Mental Disorders–5. Current Opinion in Psychiatry, 25(1), 52-58. DOI: 10.1097/YCO.0b013e32834c3f19Stoffers-Winterling, J. M., Ribeiro, J. P., Kongerslev, M. T., Völlm, B. A., Mattivi, J. T., Faltinsen, E., ... & Lieb, K. (2022). Pharmacological interventions for people with borderline personality disorder. Cochrane Database of Systematic Reviews, (11). https://doi.org/10.1002/14651858.CD012956.pub2

Medication and BPD: it’s one of the most debated, confusing, and personal topics out there. In this episode, we unpack what the research actually says about meds for BPD and what they can and can’t do.From antidepressants to mood stabilizers to the “medication merry-go-round,” we explore the science, the side effects, and our own lived experiences. Whether meds changed your life, didn’t help at all, or left you somewhere in between, this one’s for you.Trigger Warning: This episode contains frank discussion of medication, mental health treatment, and sensitive topics. Listener discretion is advised.🌱 Have questions, stories, or something you’d like us to cover? We’d love to hear from you. Email us at [email protected]⁠⁠⁠⁠⁠ and let’s keep the conversation going.🎧 Looking for meditations made for emotional regulation, BPD, and more? Check out  Empowered Heroes Meditations  on ⁠⁠⁠⁠Spotify.If you’d like more support in your journey toward BPD recovery, Steff offers 1:1 sessions using evidence-based tools from DBT and Mindfulness to help you heal. Email for a free 30-Minute Consultation: 📩 [email protected] or check out the website: www.bpdsupport.org📚 Referenced Research Includes:Bohus, M., Haaf, B., Simms, T., Limberger, M. F., Schmahl, C., Unckel, C., ... & Linehan, M. M. (2004). Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: a controlled trial. Behaviour research and therapy, 42(5), 487-499. https://doi.org/10.1016/S0005-7967(03)00174-8Crawford, M. J., Sanatinia, R., Barrett, B., Cunningham, G., Dale, O., Ganguli, P., ... & Reilly, J. G. (2018). Lamotrigine for people with borderline personality disorder: a RCT. Health Technology Assessment (Winchester, England), 22(17), 1.doi: 10.3310/hta22170Ingenhoven, T., Lafay, P., Rinne, T., Passchier, J., & Duivenvoorden, H. (2010). Effectiveness of pharmacotherapy for severe personality disorders: meta-analyses of randomized controlled trials. J Clin Psychiatry, 71(1), 14-25. 10.4088/JCP.08r04526greLieb, K., Völlm, B., Rücker, G., Timmer, A., & Stoffers, J. M. (2010). Pharmacotherapy for borderline personality disorder: Cochrane systematic review of randomised trials. The British Journal of Psychiatry, 196(1), 4-12. doi:10.1192/bjp.bp.108.062984National Institute for Health and Care Excellence (NICE). (2009). Borderline personality disorder: recognition and management. Clinical guideline [CG78]. https://www.nice.org.uk/guidance/cg78Ripoll, L. H. (2012). Clinical psychopharmacology of borderline personality disorder: an update on the available evidence in light of the Diagnostic and Statistical Manual of Mental Disorders–5. Current Opinion in Psychiatry, 25(1), 52-58. DOI: 10.1097/YCO.0b013e32834c3f19Stoffers-Winterling, J. M., Ribeiro, J. P., Kongerslev, M. T., Völlm, B. A., Mattivi, J. T., Faltinsen, E., ... & Lieb, K. (2022). Pharmacological interventions for people with borderline personality disorder. Cochrane Database of Systematic Reviews, (11). https://doi.org/10.1002/14651858.CD012956.pub2

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Is There a Pill for BPD?

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This episode was published on October 24, 2025.

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Medication and BPD: it’s one of the most debated, confusing, and personal topics out there. In this episode, we unpack what the research actually says about meds for BPD and what they can and can’t do.From antidepressants to mood stabilizers to the...

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