Itching for Answers: Understanding PN Inside Out

Dr. Shannon Trotter sits down with Dr. Shawn Kwatra, a leading expert on chronic itch, to shed light on prurigo nodularis (PN)—a painful, often misunderstood condition frequently misdiagnosed as psychological.Dr. Kwatra explains that PN is driven by a systemic inflammatory cycle between the immune system and nerves, creating an itch patients describe as worse than pain. He shares new insights into diagnosis, mental health impact, and cutting-edge treatments, including two FDA-approved biologics—dupilumab and nemolizumab—that offer real relief.This episode brings awareness, compassion, and hope to those living with PN—and to the clinicians working to better treat it.