iwCAR-T Session II: Cell therapies in GU cancers

The 5th International Workshop on CAR-T (iwCAR-T) took place in Scottsdale, AZ, on 14 – 16 April 2023, and brought together world-leading experts in CAR-T therapy as they discussed the latest in the field. In this podcast series, you will gain an insight into the sessions that took place at this year’s meeting, which covered the latest updates in CAR-T therapy in solid tumors, as well as associated challenges. Join Vivek Narayan, Saul Priceman, and Nicholas Zorko in this compelling podcast episode recorded during the iwCAR-T meeting. Focusing on genitourinary malignancies, particularly prostate and urothelial cancer, the experts discuss the promises and hurdles of NK cell therapies, unresolved questions surrounding NK cell infiltration and manufacturing as well as obstacles in engineering T cells for the immunologically cold environment of prostate cancer. Insights into the role of lymphodepletion chemotherapy and the advantages of targeting B7-h3 as an antigen in prostate cancer are also explored.