EPISODE · Nov 8, 2024 · 0 MIN
今日肿瘤学最高分文献 - 2024-11-08
from 萌喵读文献-肿瘤学 · host Meng Zhao
欢迎收听医学新发现！今天，我们要探讨的是Nature杂志的一项突破性研究，揭示了癌细胞中的额外染色体DNA（ecDNA）与治疗抵抗和预后不良的关系。研究分析了近15000名患者的近40种肿瘤样本，发现17.1%的样本含有ecDNA。这些ecDNA不仅放大了致癌基因，还经常放大调节免疫反应的基因，导致肿瘤T细胞浸润减少。这项研究不仅揭示了ecDNA的临床重要性，还为癌症治疗提供了新的视角。不要错过这一突破性的医学进展！
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