Journal club: Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis

A combination of prednisone, azathioprine, and N-acetylcysteine has been widely used as a treatment for idiopathic pulmonary fibrosis, however the safety and efficacy of this three-drug regimen is unknown. Jennifer Quint, Thorax’s Journal Club editor, talks to Fernando Martinez, Professor, Department of Internal Medicine, University of Michigan, Ann Arbor, about the controversy surrounding the question, and what his paper on it reveals. See also: http://www.nejm.org/doi/full/10.1056/NEJMoa1113354