July 2025 Research Roundtable: Fibrosis and its Impact on Lipedema with Dr. David Amron

“It’s a really cool time to be in this field,” said Dr. David Amron during July’s Research Roundtable, hosted by Dr. Karen Herbst.This session drew a record number of questions from an engaged audience of both patients and clinicians, reflecting the strong interest in the topic: fibrosis in lymphedema and lipedema.This is a particular area of expertise for Dr. Amron, who has performed over 10,000 successful surgeries and developed the Advanced Lipedema Treatment (ALT) Program at The Roxbury Institute. His approach combines an advanced application of the tumescent technique with a meticulous focus on operating within the “safe plane”—a surgical zone that minimizes risk while maximizing precision. This method is especially effective in addressing the dense, fibrotic fat tissue associated with lipedema.Dr. Amron emphasized that, with lipedema, too often the focus is on fat rather than fibrosis. He suggests that targeting fibrosis can significantly improve tissue decongestion, giving the tissue “a new start.” The discussion also explored key questions: Does fibrosis drive fat cell growth? Why is it so painful? And what role do conditions like leaky gut and mast cell activation syndrome play in these chronic conditions?Topics ranged from abdominal lipedema to the use of GLP-1 medications before and after surgery, as well as why pneumatic compression therapy is a consistent part of Dr. Amron’s treatment plans. Despite the hour-long session, many questions remained—underscoring the complexity and importance of this topic.The Lympha Press Research Roundtable is a free monthly event that brings leading-edge information to patients and clinicians alike. Learn more at www.lymphapress.com.This Roundtable was originally recorded live on July 7, 2025. The views and opinions expressed in this program are those of the speakers and do not necessarily reflect the opinions or positions of Lympha Press. The content is for educational purposes only and not intended as medical advice.Watch more Roundtables from our Lympha Press Research Roundtables playlist on YouTube.