EPISODE · Apr 14, 2025 · 18 MIN
【抗衰】长寿通路相关及槲皮素哪里来.m4a
from 恰好我知道
参考文献(找不到我的微信滴:A2016A05A) 1. Campisi, J., Kapahi, P., Lithgow, G. J., Melov, S., Newman, J. C., & Verdin, E. (2019). From discoveries in ageing research to therapeutics for healthy ageing. *Nature, 571*(7764), 183-192. doi.org 2. Justice, J. N., Nambiar, A. M., Tchkonia, T., et al. (2019). Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study. *EBioMedicine, 40*, 554-563. doi.org 3. López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. *Cell, 153*(6), 1194-1217. doi.org 4. Sinclair, D. A., & LaPlante, M. D. (2019). *Lifespan: Why We Age—and Why We Don’t Have To.* Atria Books. 5. Zhu, Y., Tchkonia, T., Pirtskhalava, T., et al. (2015). The Achilles’ heel of senescent cells: From transcriptome to senolytic drugs. *Aging Cell, 14*(4), 644-658. doi.org 说明: - Campisi 2019 :系统总结了衰老生物学与治疗策略。 - Justice 2019 :达沙替尼+槲皮素(D+Q)的首个人体临床试验。 - López-Otín 2013 :经典衰老标志理论框架。 - Sinclair 2019 :书籍,涵盖NAD+/Sirtuins与抗衰老机制。 - Zhu 2015 :首次提出Senolytics概念及D+Q联用策略。 在小宇宙查看该单集文稿
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