"Kidney Doctor: The Brutal Truth About " The Brutal Truth About IgA Nephropathy Part1 episode artwork

EPISODE · May 7, 2026 · 3 MIN

"Kidney Doctor: The Brutal Truth About " The Brutal Truth About IgA Nephropathy Part1

from Kidney Wellness with Dr. Bismah · host Bismah Irfan, MD

In this episode, we take a deeper look at the mechanism behind IgA nephropathy — a condition driven by a defective immune protein (IgA1) that originates in the gut.We also examine how treatments like Tarpeyo are designed to target immune activity in the small intestine — and why that raises a critical, often overlooked question: what’s activating the immune system there in the first place?We explore the role of the gut microbiome, chronic infections, and mucosal immune triggers in driving abnormal IgA responses. From oral and tonsil-related infections to gut imbalances and pathogens like Helicobacter pylori, emerging research suggests these upstream factors may play a meaningful role in how the disease develops and progresses.Follow & Subscribe:Youtube: www.youtube.com/@drbismah Facebook: https://www.facebook.com/KidneyHealthMD Instagram:https://www.instagram.com/kidney.healthmd/ LinkedIn: https://www.linkedin.com/in/drbismah/ Website: https://www.drbismah.com/about/

Episode metadata supplied by the publisher feed · Published May 7, 2026

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