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Kidney Failure: It is Damaged Mitochondria episode artwork

Nov 29, 2025 33 min

Kidney Failure: It is Damaged Mitochondria

from Mitolife Radio Hosted by Matt Blackburn

I receive a lot of health questions about how to remedy various debilitating conditions. One of the more concerning questions I receive frequently is regarding kidney failure. Why is there an epidemic of people with failing kidney function? It comes down to mitochondria dysfunction. Instead of focusing in one one study like most health educators do, my goal with these short shows is to paint broad strokes and cover the entire subject from a birds eye view all the way down to the mitochondrial level. Most importantly, as I cover various health conditions in future episodes, I will focus very heavily on the solutions, citing research and mechanisms to back up each of the proposed supplements or protocols. In the case of the kidneys, it comes down to one protein: mitochondrial transcription factor A, or TFAM. When that critical protein inside mitochondria in your kidneys becomes deficient, energy production falls and tissue function decreases, hence, kidney failure. It always comes back to mitochondria. My website: www.matt-blackburn.com Mitolife products: www.mitolife.co Music by George Henner: https://georgehenner.bandcamp.com Two studies I referenced: Mitochondrial Energetics in the Kidneys https://pmc.ncbi.nlm.nih.gov/articles/PMC5965678/#:~:text=The%20kidney%20is%20one%20of,pressure%20in%20the%20glomeruli5. Loss of Mitochondrial Transcription Factor A (TFAM) in Tubule Cells Causes Renal Failure https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3346980

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