KOL Conversation on EOE

Join Dr. Amit Patel and Dr. Gary Falk as they recap key highlights from the Eosinophilic Esophagitis (EoE) Disease State Summit, held live at GI ReConnect in Colorado. This expert-led discussion explores best practices in the evaluation, diagnosis, and management of EoE. The panel emphasizes updates from the ACG guidelines, including the importance of performing index endoscopy off therapy, standardized scoring tools like EREFS and the EoE Index of Severity (EoE-IS), and the nuanced role of histology in guiding treatment. They discuss differentiating EoE from GERD, appropriate biopsy practices, and integrating pathology features such as lamina propria fibrosis and microabscesses into reporting. The conversation dives into shared decision-making, a key principle in selecting between PPIs, topical steroids, elimination diets, and biologic therapy such as dupilumab. The faculty also review maintenance strategies, dilation techniques, response assessment timelines, and the potential for loss of therapeutic effect. Looking ahead, they highlight ongoing challenges in phenotyping, treatment personalization, and the expanding pipeline of novel agents. Whether you're a gastroenterologist, allergist, or APP managing EoE, this is a must-watch for optimizing care in this evolving space.