KOL Conversation on IBS

Join Dr. Satish Rao, Dr. Andrea Shin, and Dr. Ali Rezaie, for a comprehensive roundtable discussion on the evolving landscape of irritable bowel syndrome (IBS), recorded live at GI ReConnect. This engaging conversation explores evidence-based management strategies for both IBS with constipation (IBS-C) and IBS with diarrhea (IBS-D), covering dietary interventions, first-line therapies, FDA-approved medications such as linaclotide, lubiprostone, tenapanor, and rifaximin, and the growing role of neuromodulators in managing chronic pain. The faculty also discuss diagnostic tools including anorectal manometry and breath testing, the importance of identifying pelvic floor dysfunction and small intestinal bacterial overgrowth (SIBO), and the impact of psychological comorbidities, pelvic pain, and hormonal disorders on IBS outcomes. Additional highlights include commentary on emerging therapies such as microbiome-targeted interventions, fructo-oligosaccharide-based prebiotics, and investigational drugs like OPS-2071 and crofelemer. Emphasizing the importance of personalized care and multidisciplinary collaboration—including GI psychology, gynecology, and nutrition—this session offers clinicians practical insight into tailoring treatment plans to patient goals and symptom patterns while previewing the future of precision medicine in IBS care.