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May 15, 2026 27 min

Lessons From the Hantavirus Outbreak

from The Daily Hosted by The New York Times

Inside a hospital in Nebraska, 16 Americans who may have been exposed to the hantavirus have begun an unusually long quarantine. In some cases, it will last up to 42 days. Apoorva Mandavilli, who covers global health for The New York Times, explains what is known about the deadly outbreak and how the public heath system responded. Guest: Apoorva Mandavilli, a science and global health reporter at The New York Times. Background reading: American passengers exposed to the hantavirus began their quarantine in the United States on Monday. Here’s what to know about the hantavirus outbreak on the cruise ship. Photo: Chris McGrath/Getty Images For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday. For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday. Subscribe today at nytimes.com/podcasts or on Apple Podcasts, Spotify and Amazon Music. You can also subscribe via your favorite podcast app here https://www.nytimes.com/activate-access/audio?source=podcatcher. For more podcasts and narrated articles, download The New York Times app at nytimes.com/app.

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Sixteen Americans are isolating at a special quarantine center in Omaha, including one person who tested “mildly” positive for the virus.

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Lessons From the Hantavirus Outbreak

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Good morning, everyone. It is my second day here at the National Quarantine Unit in Omaha, Nebraska. And I just want to give you a little tour of my room. From New York Times, I'm Michael Barrow. This is a daily.

So this is the door where I've only entered once because I will not be exiting. Inside a hospital in Nebraska, 16 Americans who have been exposed to the Hunter Virus aboard a cruise ship have begun an unusually long quarantine that in some cases will last up to 42 days. This is the one bag I was able to bring, and I shoved socks, underwear, shorts, and things throughout the bag where I had space. I prioritized my electronics like. Medical officials say that precaution is required to protect the public from a little understood disease that has already proven highly fatal to those onboard the ship.

So my thought is, I know that if anything were to happen, I can't just either be anywhere else to have better medical care for this specific illness I'm being here. Today, approval mandavili on what we're learning about that outbreak, the virus behind it, and how a public health system, still reeling from COVID, responded to the crisis. 98.6, now I have to put on my mask so I can show the nurses that it comes to us all good. It's Friday, May 15th. Appuavo, welcome back to the daily.

Thanks for having me. Always a pleasure. It feels like in our post-COVID world where every virus that you hear about inevitably resurrects the ghost of the pandemic, this latest outbreak on a ship that this has really consumed all of our imaginations and kept a few of us up at night. Understandably, I mean, as you mentioned, the ship, but also a virus that most of us have not really spent much time thinking about and we're hearing about people getting sick one after the other. The numbers are going up.

We're hearing all those words quarantine, isolation, contact tracing, death. Death, yeah. And we have PTSD, many of us from having dealt with COVID. So yeah, I'm getting a lot of panicked messages from friends and family. My son, my daughter's best friend freaking out.

Is this the next pandemic? Are we all going to die? You give too many people yourself on. Maybe. And what do you tell these people when they reach out to you over the past two weeks about what began on this ship?

I have said consistently the same thing over the past two weeks, which is this is not the next pandemic. And I say that because we may not know a ton about this virus, but we know enough to know that it does not spread easily. It's not super contagious. And in fact, this is the only kind of this antivirus that even spreads among people at all. And so there are just a lot of signs from what we know so far that do indicate that this thing is going to stay contained.

But I don't want to minimize the fact that we have had 11 cases so far, three deaths, and there will probably be more cases. And this is a serious outbreak. And it's a serious disease. There's a very high fatality rate once people do get sick. And so the experts I talked to are worried, but they're worried mainly for the people on the ship, not for the rest of us.

And they are also sort of relieved that this outbreak happened on a cruise ship because it means that it's a lot easier to track all of those folks and to contain the outbreak, which they're doing right now. Interesting. I don't think of that ship as being a lucky situation, but it sounds like in a way it was the best possible scenario for an outbreak like this. Right. From a global perspective, if you want to have an outbreak, it's best to have it on an isolated cruise ship from where you can trace people.

Well, let's talk about that ordeal on that ship. With the benefit of a lot of reporting now that you and our colleagues have done, tell us as best you can the story of what happened on that ship with this virus, and ultimately what it's taught us about this disease. A lot of us didn't really know much about until now. Yeah. So the cruise ship is designed for polar expeditions and it's set off from Ushawaya.

I've been there actually. It's a gorgeous city. It's called literally the end of the world because it's the southernmost tip of the Americas. And people set off on this cruise. We're interested in things like bird watching and looking at the animals that live in these kinds of conditions.

And this couple, this Dutch couple, we think, went bird watching in a lot of different places in Argentina and Chile and Uruguay. And the World Health Organization is still trying to figure out exactly where in that process they might have become infected. But the current theory is that at least the husband and possibly the husband and the wife got infected from a rodent and became infected with antisvirus, which is a kind of hunter virus, a species of hunter virus that's only found in Argentina. And what's the working theory for how they would have gotten this virus from a rodent in Argentina? Like kind of logistically?

Well, we don't know exactly how, but most likely they got it by being in touch with rodent droppings or with yourin. Maybe they touched an object that had those things on it and then they put their fingers in their mouth. We don't know exactly how. And if we're, is this any old rodent or something quite specific? Something quite specific. So in Argentina, it's from the long tail to pig me rat.

And there are other rodents that may transmit it, but none of them are the mouse that you might see in your house. Got it. Okay. So this couple is exposed, we think to this virus, and now they're on this boat. Right. And then the husband starts to feel a little sick.

And then he starts to get sicker and on April 11th, so 10 days after they've left the shawaya, he dies. This is my side beauty. To modify the passing clues. Suddenly passed away last night. And they make this announcement. They tell the other passengers that we have somebody on the

boat who has died, but no one panics because people do die on cruise ships sometimes. And this man was 70 and who knows what he died of. Heart attack, stroke, whatever. Exactly. And so they continue on. And also, remember, they're going through some very remote parts

of the world. They're in the middle of the ocean. There's no land nearby. And so the body stays on the ship. In the ship's morgue.

In the ship's morgue. They continue on until April 24th. They reach St Helena, which is an island in the South Atlantic. And when they get there, that's when the body's taken off the ship. And the wife of this guy also is a marks along with another 30 or so people.

And she then flies to Johannesburg in South Africa. She's Dutch, so she's trying to get on a flight from Johannesburg to Amsterdam then. Gets so sick that she's made to get off the flight. She doesn't fly. She stays in Johannesburg and she dies.

Wow. The people on the ship also hear about her. Now, a second person has died. People on the boat understand that. Do they start to get a little bit worried?

Not yet. According to the people on the ship who have talked about this, they didn't even really worry that much when a third person got sick and had to be taken off the ship medical evacuation on April 27th. They were still thinking, oh, maybe this is COVID. Maybe this is a flu. Right.

Could be so many other things. You know, it's like that old adage when you hear hooves think horses, not zebras. No one's thinking zebra. I don't think some weird, huntivirus that no one's heard of. But then as more people start to get sick, the ship's doctor gets sick and other patients get sick. And then most importantly,

on April 28th, another person died. A third passenger died, an 80-year-old German woman, who had not had that much contact with the couple as far as anyone can tell. That's when everyone starts to get worried. And then a few days later, on May 2nd, when you finally have a test saying that this is a huntivirus, this particular kind of huntivirus causes a very severe respiratory illness. Basically, people start out with symptoms that seem very much like a flu, but then what they eventually die off is pneumonia. Their lungs fill up with fluid

and can also send their immune system into overdrive. And so that can actually be what kills the patient in the end. And are there any treatments? Not yet. So at this point, with huntivirus confirmed on the ship.

Thank you for joining us for this briefing on the Hanta virus situation. That's when the World Health Organization gets involved. Given the incubation period of the Andis virus, which can be up to six weeks, it's possible that more cases may be reported. All of a sudden, you have this more global event in countries all around the world are paying attention. This is when this story starts to really explode.

Right. And according to all this is happening, and the world is waking up to what's happening on this ship, what is the theory, especially in the public health world, at places like WHO, about how these passengers are getting sick? I recall very amateur hour over here thinking, oh, there must be rodents on this ship. I'm sure all ships have rodents. Is that what's going on?

Well, that's not out of the question, right? They could have gotten it that way. But as soon as scientists realize that this was the Andis virus species of Hanta virus, for which we do know human-to-human transmission as possible, they immediately started considering that as a possibility. That instead of all these people getting it from rodents on the ship, there was somebody who brought it on board, like the Dutch couple probably did now. Right. They could have been patients 0 and 1.

Right. And that they may have then passed it on to everybody else. And so that very quickly became a working theory, and the WHO and the European CDC and a Dutch official, they were on board interviewing people, trying to figure out what was happening. And then finally, the WHO negotiates with the Spanish government to have the boat dock in the Canary Islands. The passengers get off there, and all of the health officials from various countries take the passengers to their countries, take them home for monitoring.

The question on everyone's mind from really the moment this began is just how big a risk is this virus that's quite clearly being passed around the ship. So what are these public health officials around the world saying about that risk level? So immediately, the WHO and everybody else was actually speaking, is very attuned to the fact that we all have post-COVID PTSD. I do some of them, actually. This is not the start of a COVID pandemic. This is an outbreak that we see on a ship.

And they immediately start saying, calm down, or nothing bad is going to happen. The risk to you is very, very low. This is not the same situation we were in six years ago. The CDC actually says nothing, really, until May 9th. This is America's premier public health agency.

Correct. And they stayed silent on this matter until... Despite the fact that there are many Americans on that ship. Despite the fact that Americans on that ship, despite the fact that American media is carrying news of the ship and these cases and this outbreak, nothing from them, until May 9th. Here with more information is NIH Director and Acting CDC Director, Dr. J. Badacharya.

And then finally, that weekend, J. Badacharya, who is the Acting Director of the CDC, went on box and he went on CNN. And he said, Well, I mean, you think about cruises. It's close quarters, right? It's only spreads when there's close contact. Don't worry.

Don't worry. You have to be in close contact with someone who has a lot of symptoms. There have been eight people that have infected. The first two were probably breathed up mouse droppings in Argentina. And then people who were very close to them, you know, the roommates, a doctor who was caring for them.

They're the ones who got symptomatic. He said roommates got infected. That's not true. It's not true at all. They were in their 80s.

They were in their 80s. They were in their 80s, which is also not true. Unfortunately, they died. The problem with that is that the overall message of you don't need to worry is probably accurate, but it's a lot more complicated than that. We know from previous outbreaks of the virus and even from this current outbreak that it can actually spread even when there is a close contact.

And so there was a lot of missing nuance in the communication. And it seemed like not just Dr. Padacharya and the CDC, but even the WHO, even some of these other health officials were in trying to not get people to panic skimming over all of those and just getting right to this is not a pandemic. We're back. So, let's talk about the nuances that have been glossed over so far.

Because in the days since this outbreak began, you've assigned yourself to read all the research on this virus. You've called a lot of medical experts. You've been trying to really objectively understand this virus and its transmissibility and risk. And so what have you found and how does that line up with how public health officials have been talking about it? What you've been hearing from public health experts is very different from how the experts that I've been calling talk about it.

One thing that public health officials have been saying over and over is that this virus only spreads through closed sustained contact. But actually the best report we have of an outbreak suggests that at least sometimes you don't need close contact. So the best characterized outbreak is this outbreak that happened in Argentina in 2018. And in that outbreak, 34 people got sick and 11 people died. But the interesting thing about that outbreak is that it began with one person who got sick from rodents, went to a birthday party when they were feeling sick.

And he infected five people at that party. So that this birthday party, for example, someone got infected just in passing them saying hello, a couple of other people that infected sitting at tables at this birthday party near someone who was infected. So there wasn't this closed sustained contact we've been hearing about. So what you have found suggests a level of transmissibility that involves more casual contacts than what health officials indicated when this latest outbreak began. They seem to be suggesting you need pretty intimate, close contact.

And what you're describing is not that. It's not that. But I do want to be careful to say that we don't think that happens very often. I think all of these circumstances have to be just right. It seems like that only happens when somebody's on the first day of symptoms, for example.

And also in that same study, the people who were sick were being treated by 84 health care workers. None of them got sick, even though many of them weren't wearing the right PPE. So it's not necessarily that this virus is spreading really rapidly or really efficiently. It's just that if you have all the right circumstances, it can spread by casual contact. Well, let me get a little technical here.

And I learned this from you during COVID. What is the rate of transmissibility of this virus? What is it? It's R-Naught. Very impressive.

So remember this? The R-Naught in that outbreak that I just described, where there were those super spreading events, was 2.1, which is not super high. If you compare that to COVID in the early days, it was probably around three. But as the coronavirus mutated by Amacron, we were talking about an R-Naught of 10. Right.

One person who had COVID could basically transmit it to up to 10 other people. Right. And measles, we think, has an R-Naught of up to 18. So when we look at those very contagious viruses, 2.1 is not crazy high. Right.

But at the same time, that last outbreak, and this new one, strongly suggests a high fatality rate. Right. In that case, it was 34 people infected, 11 dead. That's about a third roughly. In this case, you have 11 people infected, so far, of which three died, again, about 30%.

That's higher than COVID. It's much higher than COVID. And that's partly why some of these public health officials are so worried, because even if it spreads rarely, it is a serious disease, it's a severe disease. But again, I want to introduce one slight note of uncertainty here, which is we may not know the exact fatality rate for this virus, because if people are infected but don't have symptoms, maybe we've missed some cases in the past, and we've actually overestimated that. That's interesting.

Well, given all of this information, I'm quite curious if health officials around the world were able to locate every one of the boat's passengers and prevent them from infecting two additional people somewhere out there in the world. And especially those who got off the boat early before it was understood what was happening. Yeah, they have now figured out who got off the boat and who needs to be monitored. And they're, in fact, also trying to trace the contacts of all those people. Like if somebody got off the boat and then flew to Johannesburg and then flew elsewhere, like who was on that flight.

So we should expect to hear more about people being monitored and people getting confirmed positives as people go through the full incubation period, which for this virus can be up to eight weeks, but for most people, it'll be more like 42 days, six weeks. Which is quite long. It's very long for people to have to quarantine or self-isolate or be monitored for symptoms. Does that contact tracing literally involve telling people on a plane? It's possible that you may have sat next to one row back from somebody who is infected with this virus.

That is actually what happens. I believe actually they're considering anybody high-risk if somebody sat within two rows, the CDC's guidance of someone who was on the cruise ship. And so they are doing whatever they can to locate everybody who may have come into contact with the passengers on the cruise ship. And of course, the passengers themselves are also being very carefully monitored. Got it.

Speaking of the CDC, what has been its track record of contact tracing in the US specifically? And I ask that because it's not entirely a secret. You've been on the show talking about it. The Centers for Disease Control and Prevention in the US in the second Trump administration has experienced a tremendous amount of turnover resignations and a real sense of kind of a post-COVID backlash from the folks at the White House will oversee this CDC. So how engaged have they been and effective have they been?

The CDC was never on that ship. There were officials from the WHO, from the European CDC, from the Dutch Health Ministry. Who made their way onto it. Who made their way onto it. And who were interviewing the people on the ship asking about their contacts and so on.

The CDC was not there. The CDC is not really even allowed to talk to the WHO on a regular basis, although they are doing that now during this outbreak because the US withdrew from the WHO. And so I actually just spoke to a WHO official who was describing how sad it is that the CDC was not a part of it because they are the world's experts. The CDC is a force, this official said. We need them to tell the rest of the world about all the things that go into an outbreak.

They were not really engaged until pretty late in the process. And once they did become engaged, how did they do? It seems like things are going well now. The CDC did go to the Canary Islands where the boat eventually docked and the American passengers were all brought back to the US to Omaha, Nebraska. Right. We heard from one of the people who is now in quarantine there.

Correct. And so they're very closely monitoring the situation now and seem to be extremely engaged. And if they're engaged now and it's going well, how important is it ultimately that they were a little slow out of the gate? In an outbreak, time is everything. We got like this time.

It's a cruise ship. It's not a virus that's spread super easily. But what about next time or the time after that? If there is a virus that spreads very easily, we're not going to have time to be slow. So, Aprava, if we use this outbreak as a case study and we tend to use all outbreaks in public office case studies, what do you think officials have learned and not learned in our post-COVID world?

I think we've learned a lot of technical things. And I say that not just about the public health officials, but also us, right? Like things like R-NOT. We all have a better understanding of what happens during an outbreak. And so things like contact tracing and thinking about vaccines and treatments, those I think are pretty good.

But I think where we really have not learned is communication because I still don't really hear public health officials saying enough about what they know and what they don't know. What I still hear is them projecting a lot of confidence and wanting to reassure people when actually there's still quite a bit of uncertainty. I think overall they're right. I think this is not a pandemic and we don't need to worry. But I think they can still be a lot more honest about all the things that they're still learning about this virus.

Right. And in that scenario, perhaps someone from CDC comes out and says, look, we don't think the risk of this ever getting to you is high. We think it's low. But our original thinking about close contact, we might need to revise that. We still don't think it's a risk to you, but we are learning new things about this virus.

You're saying essentially treat us like adults. Treat us like adults and tell us that as soon as you find out, you will tell us. We have officials now who made it their business, so even became famous by criticizing the CDC for how it did its job before, for saying things like six feet of distance and things like that. They criticized the CDC saying there's no evidence for those things. And yet here we are in another outbreak.

And those people are now in power and they're making some of the same mistakes. Well, Brava, thank you very much. We should have. Thank you. It's always a pleasure.

On Thursday afternoon, US officials said that they are now monitoring a total of 41 people across the country for hunt of virus symptoms, including 16 people who traveled on a plane with somebody known to have been infected. We'll be right back. Here's what else you need, gender day. During a hearing on Thursday, the head of the US military's central command, Brad Cooper, told senators that the US military had a near perfect record of avoiding civilian casualties in Iran, a claim human rights groups and some lawmakers rejected as not remotely credible.

So how do you explain the publicly available information that 22 schools have been hit and multiple hospitals? There's no way that we can corroborate that. Several senators, including Democrat Kirsten Gillibrand of New York, pressed Cooper on the reports, including in the New York Times, that US attacks have damaged nearly two dozen Iranian schools and 17 Iranian health care facilities. Have you investigated those claims? We have not.

Why have you not investigated those allegations when they're publicly being made on the cover of the New York Times? Yeah, Cuba says it has run out of oil, a dire situation likely to plunge the country into even bigger and longer blackouts. The crisis largely stems from crumbling infrastructure and an energy blockade imposed by the Trump administration, which is seeking political reforms across Cuba. Cuba is now without electricity for as many as 22 hours a day. Today's episode was produced by Nina Feldman, Alex Stern and Jack Desiderot.

It was edited by Michael Benoit with help from Lisa Chow and contains music by Mary and Lozano and Alicia Beitou. Our theme music is by Wonderly. This episode was engineered by Alyssa Moxley. Special thanks to Sonia Rau. That's it for daily. I'm Michael Borrow. See you on Sunday.

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