Life's Catalyst: RNA with Thomas Cech [Ep. 423] episode artwork

EPISODE · Jun 4, 2024 · 57 MIN

Life's Catalyst: RNA with Thomas Cech [Ep. 423]

from Into the Impossible With Brian Keating · host Big Bang Productions Inc.

Join my mailing list https://briankeating.com/list to win a real 4 billion year old meteorite! All .edu emails in the USA 🇺🇸 will WIN! How did life begin? What makes us human? Why do we get sick and grow old?  For more than half a century, we've searched for answers to these questions in DNA. But after a series of groundbreaking discoveries, attention has turned to RNA, the long-overlooked molecule that is now at the heart of biology's greatest mysteries. Here today, to shed light on this topic, is none other than the Nobel laureate Thomas Cech. Thomas shared the 1989 Nobel Prize in Chemistry with Sidney Altman for their discovery of the catalytic properties of RNA. He discovered that RNA could cut strands of RNA itself, suggesting that life might have started as RNA, and found that RNA can not only transmit instructions but also speed up the necessary reactions.  His upcoming book, The Catalyst, promises to bring years of pioneering research to the forefront, demonstrating how RNA holds the key to understanding life on Earth—from its very origins to our future.  Join us as we explore the most transformative breakthroughs in biology and beyond on this episode of Into the Impossible!  Key Takeaways: 00:00 Intro 01:17 What is life? 02:05 Judging a book by its cover 05:44 Does profit drive innovation?  10:51 The RNA breakthrough  14:40 Is DNA a one-trick pony? 24:54 Panspermia, DNA and RNA 29:25 RNA’s role in the end of life 37:01 CRISPR  42:09 Are DNA and RNA the only two informational molecules?  46:57 The future of education  51:38 The greatest thing humans have ever done 53:08 What Thomas has been wrong about 54:22 Outro — Additional resources: 📝 Get one month of Snipd Premium for free with this link: https://get.snipd.com/Cx7S/brianSnipd Snipd lets you take Smart Notes 🧠 with AI 💡 — it’s my favorite podcast player 😀 ! ➡️ Learn more about Thomas Cech: 💻 Nobel Prize: https://www.nobelprize.org/prizes/chemistry/1989/cech/facts/   📚 Get The Catalyst on Amazon: https://a.co/d/9oaErgg ➡️ Follow me on your fav platforms: ✖️ Twitter: https://twitter.com/DrBrianKeating  🔔 YouTube: https://www.youtube.com/DrBrianKeating?sub_confirmation=1  📝 Join my mailing list: https://briankeating.com/list  ✍️ Check out my blog: https://briankeating.com/cosmic-musings/  🎙️ Follow my podcast: https://briankeating.com/podcast Into the Impossible with Brian Keating is a podcast dedicated to all those who want to explore the universe within and beyond the known. Make sure to subscribe so you never miss an episode! Learn more about your ad choices. Visit megaphone.fm/adchoices

Join my mailing list https://briankeating.com/list to win a real 4 billion year old meteorite! All .edu emails in the USA 🇺🇸 will WIN! How did life begin? What makes us human? Why do we get sick and grow old?  For more than half a century, we've searched for answers to these questions in DNA. But after a series of groundbreaking discoveries, attention has turned to RNA, the long-overlooked molecule that is now at the heart of biology's greatest mysteries. Here today, to shed light on this topic, is none other than the Nobel laureate Thomas Cech. Thomas shared the 1989 Nobel Prize in Chemistry with Sidney Altman for their discovery of the catalytic properties of RNA. He discovered that RNA could cut strands of RNA itself, suggesting that life might have started as RNA, and found that RNA can not only transmit instructions but also speed up the necessary reactions.  His upcoming book, The Catalyst, promises to bring years of pioneering research to the forefront, demonstrating how RNA holds the key to understanding life on Earth—from its very origins to our future.  Join us as we explore the most transformative breakthroughs in biology and beyond on this episode of Into the Impossible!  Key Takeaways: 00:00 Intro 01:17 What is life? 02:05 Judging a book by its cover 05:44 Does profit drive innovation?  10:51 The RNA breakthrough  14:40 Is DNA a one-trick pony? 24:54 Panspermia, DNA and RNA 29:25 RNA’s role in the end of life 37:01 CRISPR  42:09 Are DNA and RNA the only two informational molecules?  46:57 The future of education  51:38 The greatest thing humans have ever done 53:08 What Thomas has been wrong about 54:22 Outro — Additional resources: 📝 Get one month of Snipd Premium for free with this link: https://get.snipd.com/Cx7S/brianSnipd Snipd lets you take Smart Notes 🧠 with AI 💡 — it’s my favorite podcast player 😀 ! ➡️ Learn more about Thomas Cech: 💻 Nobel Prize: https://www.nobelprize.org/prizes/chemistry/1989/cech/facts/   📚 Get The Catalyst on Amazon: https://a.co/d/9oaErgg ➡️ Follow me on your fav platforms: ✖️ Twitter: https://twitter.com/DrBrianKeating  🔔 YouTube: https://www.youtube.com/DrBrianKeating?sub_confirmation=1  📝 Join my mailing list: https://briankeating.com/list  ✍️ Check out my blog: https://briankeating.com/cosmic-musings/  🎙️ Follow my podcast: https://briankeating.com/podcast Into the Impossible with Brian Keating is a podcast dedicated to all those who want to explore the universe within and beyond the known. Make sure to subscribe so you never miss an episode! Learn more about your ad choices. Visit megaphone.fm/adchoices

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Life's Catalyst: RNA with Thomas Cech [Ep. 423]

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Join my mailing list https://briankeating.com/list to win a real 4 billion year old meteorite! All .edu emails in the USA 🇺🇸 will WIN! How did life begin? What makes us human? Why do we get sick and grow old?  For more than half a century, we've...

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