Lion's Mane- The fruiting body vs. mycelium debate is actually a mechanism question episode artwork

EPISODE · Apr 28, 2026 · 5 MIN

Lion's Mane- The fruiting body vs. mycelium debate is actually a mechanism question

from NutraSift: The nutraceutical innovation podcast · host Siftlink SA

Hericenones (fruiting body): smaller molecules, cross BBB, stimulate NGF in the brain. Erinacines (mycelium): larger diterpenoids, also stimulate NGF but with different potency and targets. The "fruiting body vs. mycelium" debate in the mushroom industry isn't about quality, it's about which active compound you want. That is a distinction that is not always clear to the consumers and to many companies. Publications of interest:https://pubmed.ncbi.nlm.nih.gov/26244378/https://pmc.ncbi.nlm.nih.gov/articles/PMC11172836/https://pmc.ncbi.nlm.nih.gov/articles/PMC6803874/

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