Lithium Orotate & Lithium Carbonate [ep. 127]

In this episode of the Joy Lab podcast, hosts Dr. Henry Emmons and Dr. Aimee Prasek talk about lithium orotate, a compound different from the commonly prescribed lithium carbonate used for bipolar disorder. They explore its potential advantages including better brain absorption and fewer side effects at lower doses, while also clarifying that although it should not replace prescribed medications, it may have valuable uses. The conversation also covers how lithium orotate may have a role in clinical practice for mood disorders and depression with a genetic component. The historical context of lithium's use and the repercussions of its bad PR in the past are also noted, alongside emerging research on its possible preventive role for conditions like Alzheimer's.  About: The Joy Lab Podcast is an Ambie-nominated podcast that blends science and soul to help you cope better with stress, anxiety, and depression. It's hosted by integrative psychiatrist Dr. Henry Emmons and holistic mental health researcher Dr. Aimee Prasek. The podcast is best paired with the Joy Lab App. Bonus: spread some joy and keep this podcast ad-free by donating (Joy Lab is powered by the nonprofit Pathways North and your donations are tax-deductible). Listen & follow the Joy Lab Podcast on your favorite listening app: Spotify | Apple | YouTube   Sources and Notes: Corcoran, A. C., Taylor, R. D., & Page, I. H. (1949). Lithium poisoning from the use of salt substitutes. JAMA, 139(11), 685–688. doi:10.1001/jama.1949.02900280001001 Pacholko,  A. G., & Bekar,  L. K. (2021). Lithium Orotate: A superior option for lithium therapy?. Brain and Behavior, 11, e2262. https://doi.org/10.1002/brb3.2262 Strobusch, A. D., & Jefferson, J. W. (1980). The Checkered History of Lithium in Medicine. Pharmacy in History, 22(2), 72–76. http://www.jstor.org/stable/41109216 New York Time's article about possible lithium chloride deaths.  Time article about possible lithium chloride deaths.   Please remember that this content is for informational and educational purposes only. It is not intended to provide medical advice and is not a replacement for advice and treatment from a medical professional. Please consult your doctor or other qualified health professional before beginning any diet change, supplement, or lifestyle program. Please see our terms for more information. If you or someone you know is struggling or in crisis, help is available. Call the NAMI HelpLine: 1-800-950-6264 available Monday through Friday, 10 a.m. - 10 p.m., ET. OR text "HelpLine" to 62640 or email NAMI at [email protected]. Visit NAMI for more. You can also call or text SAMHSA at 988 or chat 988lifeline.org