Loki: How to Take On the Mindset of an Explorer

(Loki S1 E1) To kickstart the series on Becoming Curious Explorers Derrick and Drew travel with Loki to visit the Time Variance Authority.  Much like Loki, we are often thrust into totally unfamiliar scenarios in life.  What does an effective approach to exploration look like?  How can we leverage our prior knowledge and mental models while constantly integrating new information to successfully explore any uncharted dimension?