Louisville vs Mississippi Spread Pick | Louisville Football News

Louisville vs. Mississippi in Nashville this Sunday is the top-tier showdown of the week — the only game with two top-25 teams. Mississippi, a six-and-a-half-point favorite, is led by first-time head coach Pete Golding, who rose through the ranks after their historic playoff run last season. But Louisville? They’ve proven they can compete with elite squads — beating Miami as underdogs last year and finishing statistically strong, with most losses decided by a touchdown or less. Coach Jeff Brohm thrives when his team’s the underdog, boasting an 11-4 record against the spread in those scenarios since 2018. With a new QB for Louisville and a defensive-minded new hire in Oxford, expect a low-scoring battle. I’m calling the Cardinals to cover and the under 55.5 points. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/31fbc4b6f53c82fe