Louisville vs Ole Miss: High-Stakes Opener

Louisville and Ole Miss face off in a highly anticipated neutral-site clash at Nissan Stadium in Nashville, kicking off the 2026 season on Sunday, September sixth at seven thirty p.m. Eastern on ABC. Both teams, expected to rank in the top twenty-five preseason, will test their mettle early. Ole Miss, despite losing coach Lane Kiffin mid-season last year, secured thirteen wins and a Fiesta Bowl appearance. Led by quarterback Trinidad Chambliss and boasting the number eighteen transfer portal class, theyre poised for another strong season. Louisville, under Jeff Brohm for three years, posted nine wins last season, their best run since 2012. With key players like Isaac Brown and Clev Lubin returning and the top transfer class at number four, theyre ready to make a splash. Their last meeting in 2021 saw Ole Miss win forty-three to twenty-four. Expect a thrilling matchup as these reloaded squads collide to launch the new campaign. Support the show:Get a discount at https://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/6f35501ae192303b