Louisville vs Ole Miss Opening Weekend Clash | Louisville Football News

College football kicks off with a high-stakes showdown: Louisville vs. Ole Miss, the only ranked matchup of opening weekend, played neutral-site in Nashville. Can the Cardinals pull off the upset? Coach Jeff Brohm’s disciplined squad boasts a strong defense and a powerful running game led by Isaac Brown, but faces a major hurdle with rookie QB Lincoln Kienholz making his debut against a physical Ole Miss front. For Ole Miss, it’s all about their defense stepping up — pressuring Kienholz, forcing turnovers, and shutting down Louisville’s offense. Despite new coaching changes, Ole Miss’s talent and experience should give them the edge in a tight, competitive battle that could set the tone for the season. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/22b16eb70dd460be