Louisville's Big Shot at SMU | Louisville Football News

Louisville’s tough opener against Ole Miss sets the stage for a high-stakes Week Three showdown with SMU — a game that could define their ACC Championship hopes. After a nail-biting loss, the Cardinals are primed for redemption at home, where they’ve struggled recently against SMU. With Vegas favoring SMU slightly but Louisville just behind, this matchup is shaping up as a potential preview of the ACC title race. A win here could catapult them into contention, while Miami looms as the clear favorite — making this clash a must-win moment for the Cards. Listen in comfort:Get a discount on a Soli Pillow: http://solipillow.com/discount/dnn. Advertise on DNN:[email protected] This is an automated, high-level news summary based on public reporting.Report issues to [email protected]. View sources & latest updates:https://sources.thednn.ai/a0c63993709b22eb